Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

被引:115
|
作者
Qureshi, AI
Choudhry, MA
Akbar, MS
Mohammad, Y
Chua, HC
Yahia, AM
Ulatowski, JA
Krendel, DA
Leshner, RT
机构
[1] Johns Hopkins Hosp, Dept Neurol, Baltimore, MD USA
[2] Virginia Commonwealth Univ, Med Coll Virginia, Dept Neurol, Richmond, VA 23298 USA
[3] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA USA
[4] Med Coll Wisconsin, Dept Neurol, Milwaukee, WI 53226 USA
关键词
D O I
10.1212/WNL.52.3.629
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We performed a retrospective multicenter chart review to compare the efficacy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IVIg) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with Mg) was associated with a superior ventilatory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was higher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).
引用
收藏
页码:629 / 632
页数:4
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