5-HT receptor agonist-antagonist binding affinity ratios as a measure of intrinsic activity, using [3H]8-OH-DPAT and [3H]MPPF as radioligands

被引：0
|
作者：
Price, GW [1 ]
Ho, M [1 ]
Scott, C [1 ]
Selkirk, JV [1 ]
Brown, AM [1 ]
机构：
[1] SmithKline Beecham Pharmaceut, Dept Neurosci, NFSP, Harlow CM19 5AW, Essex, England
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 1998年 / 125卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
58P
引用
收藏
页码：U30 / U30
页数：1
相关论文
共 50 条
  • [31] [H-3]WAY-100635 for 5-HT1A receptor autoradiography in human brain: A comparison with [H-3]8-OH-DPAT and demonstration of increased binding in the frontal cortex in schizophrenia
    Burnet, PWJ
    Eastwood, SL
    Harrison, PJ
    [J]. NEUROCHEMISTRY INTERNATIONAL, 1997, 30 (06) : 565 - 574
  • [32] Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors
    Napier, C
    Stewart, M
    Melrose, H
    Hopkins, B
    McHarg, A
    Wallis, R
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1999, 368 (2-3) : 259 - 268
  • [33] [3H]Rauwolscine: An antagonist radioligand for the cloned human 5-hydroxytryptamine(2B) (5-HT(2B)) receptor
    Wainscott D.B.
    Sasso D.A.
    Kursar J.D.
    Baez M.
    Lucaites V.L.
    Nelson D.L.
    [J]. Naunyn-Schmiedeberg's Archives of Pharmacology, 1997, 357 (1) : 17 - 24
  • [34] [3H]5-HT binding to cloned human, dog, and rat 5-HT1D and 5-HT1B receptors
    Stanton, J
    Castro, L
    MacLeod, A
    Sternfeld, F
    Street, L
    Beer, M
    [J]. ADVANCES IN SEROTONIN RECEPTOR RESEARCH: MOLECULAR BIOLOGY, SIGNAL TRANSDUCTION, AND THERAPEUTICS, 1998, 861 : 266 - 266
  • [35] In vivo binding of [3H]N-methylspiperone to 5-HT2 receptors and the effect of the 5-HT releaser, fenfluramine.
    Gifford, AN
    Gatley, SJ
    Volkow, ND
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2000, 41 (05): : 66P - 67P
  • [36] [H-3]8-OH-DPAT LABELS THE 5-HYDROXYTRYPTAMINE UPTAKE RECOGNITION SITE AND THE 5-HT1A BINDING-SITE IN THE RAT STRIATUM
    ALEXANDER, BS
    WOOD, MD
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1988, 40 (12) : 888 - 891
  • [37] The 5-HT1A receptor agonist 8-OH-DPAT modulates motor/exploratory activity, recognition memory and dopamine transporter binding in the dorsal and ventral striatum
    Nikolaus, Susanne
    Chao, Owen Y.
    Beu, Markus
    Henke, Jan
    Antke, Christina
    Wang, An-Li
    Fazari, Benedetta
    Mamlins, Eduards
    Huston, Joseph P.
    Giesel, Frederik L.
    [J]. NEUROBIOLOGY OF LEARNING AND MEMORY, 2023, 205
  • [38] Autoradiography with [H-3]8-OH-DPAT reveals increases in 5-HT1A receptors in ventral prefrontal cortex in schizophrenia
    Simpson, MDC
    Lubman, DI
    Slater, P
    Deakin, JFW
    [J]. BIOLOGICAL PSYCHIATRY, 1996, 39 (11) : 919 - 928
  • [39] Serotonin 5-HT2A Receptor Binding in Platelets from Healthy Subjects as Studied by [3H]-Lysergic Acid Diethylamide ([3H]-LSD): Intra- and Interindividual Variability
    Olav Spigset
    Tom Mjörndal
    [J]. Neuropsychopharmacology, 1997, 16 : 285 - 293
  • [40] Characteristics of agonist displacement of [3H]ketanserin binding to platelet 5-HT2A receptors:: implications for psychiatric research
    Gurguis, GNM
    Phan, SP
    Blakeley, JE
    [J]. PSYCHIATRY RESEARCH, 1998, 80 (03) : 227 - 238
12345