Pyoderma gangrenosum following isotretinoin therapy for acne nodulocystic

被引:0
|
作者
Tinoco, Maria Paula [1 ]
Tamler, Carla [1 ]
Maciel, Gustavo [1 ]
Soares, Deborah [1 ]
Avelleira, Joao Carlos [1 ]
Azulay, David [1 ]
机构
[1] IDPRDA, Dept Dermatol, Rio De Janeiro, Brazil
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中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A 19-year-old man with nodulocystic acne on baseline was treated with isotretinoin therapy. After 1 month on the medication, he developed pyoderma gangrenosum on his pubis area, arms and legs, and pathergy on a puncture site. Possible underlying diseases were excluded. The patient was started on steroids (prednisone 1 mg/kg/d) and isotretinoin therapy was withdrawn. Later the prednisone was tappered and dapsone 100 mg/daily was initiated. After 10 months of follow-up all lesions had healed and no underlying diseases developed.
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页码:953 / 956
页数:4
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