Inhibition of stearoyl-CoA desaturase 1 (SCD1) dissociates insulin resistance and obesity from atherosclerosis

被引:0
|
作者
Brown, J. Mark [1 ]
Chung, Soonkyu [1 ]
Alger, Heather M. [1 ]
Sawyer, Janet K. [1 ]
Degirolamo, Chiara [1 ]
Nguyen, Tam [1 ]
Zhu, Xuewei [1 ]
Duong, My-Ngan [1 ]
Wibley, Amanda L. [1 ]
Davis, Matthew A. [1 ]
Kelley, Kathryn [1 ]
Wilson, Martha D. [1 ]
Parks, John S. [1 ]
Rudel, Lawrence L. [1 ]
机构
[1] Wake Forest Univ, Sch Med, Winston Salem, NC 27109 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
P328
引用
收藏
页码:E93 / E93
页数:1
相关论文
共 50 条
  • [31] Stearoyl-CoA Desaturase-1 Is Associated with Insulin Resistance in Morbidly Obese Subjects
    Sara García-Serrano
    Inmaculada Moreno-Santos
    Lourdes Garrido-Sánchez
    Carolina Gutierrez-Repiso
    Jose M. García-Almeida
    Juan García-Arnés
    Jose Rivas-Marín
    Jose L. Gallego-Perales
    Eva García-Escobar
    Gemma Rojo-Martinez
    Francisco Tinahones
    Federico Soriguer
    Manuel Macias-Gonzalez
    Eduardo García-Fuentes
    Molecular Medicine, 2011, 17 : 273 - 280
  • [32] Milk fatty acid unsaturation:: Genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and acyl CoA:diacylglycerol acyltransferase 1 (DGAT1)
    Schennink, A.
    Heck, J. M. L.
    Bovenhuis, H.
    Visker, M. H. P. W.
    van Valenberg, H. J. F.
    van Arendonk, J. A. M.
    JOURNAL OF DAIRY SCIENCE, 2008, 91 (05) : 2135 - 2143
  • [33] A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse Chromosome 19
    D. E. Tabor
    Y. -R. Xia
    M. Mehrabian
    P. A. Edwards
    A. J. Lusis
    Mammalian Genome, 1998, 9 : 341 - 342
  • [34] Recent Advances in Stearoyl-CoA Desaturase 1 Inhibitors for Dyslipidemia and Obesity
    Liu, Gang
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2010, 10 (04) : 419 - 433
  • [35] Leptin and the control of metabolism: Role for stearoyl-CoA desaturase-1 (SCD-1)
    Cohen, P
    Friedman, JM
    JOURNAL OF NUTRITION, 2004, 134 (09): : 2455S - 2463S
  • [36] Investigation of (Stearoyl-CoA Desaturase 1) SCD1 Gene Polymorphism in Khuzestan Buffalo Population Using PCR-RFLP Method
    Taghizadeh, K.
    Nasiri, M. T. Beigi
    Fayazi, J.
    Bujarpoor, M.
    IRANIAN JOURNAL OF APPLIED ANIMAL SCIENCE, 2014, 4 (02): : 425 - 428
  • [37] A role for skin stearoyl-CoA desaturase-1 in obesity and diabetes
    Ntambi, James
    CHEMISTRY AND PHYSICS OF LIPIDS, 2011, 164 : S1 - S1
  • [38] A cluster of stearoyl CoA desaturase genes, Scd1 and Scd2, on mouse Chromosome 19
    Tabor, DE
    Xia, YR
    Mehrabian, M
    Edwards, PA
    Lusis, AJ
    MAMMALIAN GENOME, 1998, 9 (04) : 341 - 342
  • [39] BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism
    Xiao, Fei
    Deng, Jiali
    Guo, Yajie
    Niu, Yuguo
    Yuan, Feixiang
    Yu, Junjie
    Chen, Shanghai
    Guo, Feifan
    SCIENCE SIGNALING, 2016, 9 (428)
  • [40] DIETARY INDUCED FATTY LIVER DISEASE IS ASSOCIATED WITH DOWNREGULATION OF THE LIVER ABUNDANCE OF STEAROYL-COA DESATURASE 1 (SCD1) MRNA AND IMPAIRED LIVER PROTEIN DIMERIZATION INDEPENDENTLY OF INSULIN RESISTANCE
    Fernandez Gianotti, Tomas
    Burgueno, Adriana L.
    Soledad Rosselli, Maria
    Pirola, Carlos J.
    Sookoian, Silvia
    HEPATOLOGY, 2011, 54 : 1169A - 1169A