Ralstonia mannitolilytica sepsis: a case report

被引:8
|
作者
Owusu, Michael [1 ,2 ]
Acheampong, Godfred [2 ]
Annan, Augustina [2 ,3 ]
Marfo, Kwadwo Sarfo [2 ]
Osei, Isaac [2 ]
Amuasi, John [2 ,4 ]
Sarpong, Nimako [5 ]
Im, Justin [6 ]
Mogeni, Ondari D. [6 ]
Chiang, Hsin-Ying [7 ]
Kuo, Chih-Horng [7 ]
Jeon, Hyon Jin [6 ]
Panzner, Ursula [6 ]
Park, Se Eun [6 ]
Marks, Florian [6 ]
Owusu-Dabo, Ellis [2 ,4 ]
Adu-Sarkodie, Yaw [8 ]
机构
[1] Kwame Nkrumah Univ Sci & Technol, Dept Med Diagnost, Kumasi, Ghana
[2] Kwame Nkrumah Univ Sci & Technol, Kumasi Ctr Collaborat Res Trop Med, Kumasi, Ghana
[3] Kwame Nkrumah Univ Sci & Technol, Dept Theoret & Appl Biol, Kumasi, Ghana
[4] Kwame Nkrumah Univ Sci & Technol, Sch Publ Hlth, Dept Global Hlth, Kumasi, Ghana
[5] Agogo Presbyterian Hosp, Agogo, Ashanti Region, Ghana
[6] Int Vaccine Inst, Dept Epidemiol, Seoul, South Korea
[7] Acad Sinica, Inst Plant & Microbial Biol, Taipei, Taiwan
[8] Kwame Nkrumah Univ Sci & Technol, Dept Clin Microbiol, Kumasi, Ghana
关键词
Ralstonia mannitolilytica; Sepsis; Nonfermenting gram-negative rods; Case report; 16S rRNA; RECURRENT MENINGITIS;
D O I
10.1186/s13256-019-2235-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background Ralstonia mannitolilytica is an emerging opportunistic pathogen that is associated with severe disease, including septic shock, meningitis, and renal transplant infections. Reports on this pathogen are limited, however, especially on the African continent. Case presentation A 2-year-old Akan child was presented to a hospital in the northeastern part of Ghana with a 1-week history of fever and chills. We identified Ralstonia mannitolilytica in her blood culture using both conventional and 16S ribosomal deoxyribonucleic acid (rDNA) techniques. The patient's condition improved clinically upon treatment with cefuroxime. Conclusion Our report highlights the potential of Ralstonia mannitolilytica to cause sepsis and thus emphasizes the need for improved laboratory diagnosis and evidence for use of appropriate antibiotics in rural settings of Africa, where presumptive treatment using antimicrobial agents is rife.
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页数:4
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