Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts

被引:5
|
作者
Raspollini, MR
Castiglione, F
Degl'Innocenti, DR
Garbini, F
Coccia, ME
Taddei, GL
机构
[1] Univ Florence, Sch Med, Dept Human Pathol & Oncol, I-50134 Florence, Italy
[2] Univ Florence, Sch Med, Dept Gynecol Perinatol & Reprod Med, I-50134 Florence, Italy
关键词
D O I
10.1016/j.fertnstert.2005.02.058
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Matrix metalloproteinase-1 (MMP-1),MMP-2, and MMP-9 expression with real-time quantitative polymerase chain reaction were analyzed in endometriotic and nonendometriotic ovarian cysts. Although MMP-1 was not detected, MMP-9 and MMP-2 were expressed in all of the cysts. In particular, in five of six nonendometriotic cysts (83.3%) MMP-2 expression was higher than in endometriotic cysts. These data may represent new molecular elements helpful in differential diagnosis of endometriotic lesions.
引用
收藏
页码:1049 / 1052
页数:4
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