Staphylococcus aureus adhesion to bone matrix and bone-associated biomaterials

被引:79
|
作者
Hudson, MC
Ramp, WK
Frankenburg, KP
机构
[1] Univ N Carolina, Dept Biol, Charlotte, NC 28223 USA
[2] Carolinas Med Ctr, Baxter Orthopaed Res Lab, Dept Orthopaed Surg, Charlotte, NC 28232 USA
关键词
Staphylococcus aureus; microbial surface component recognizing adhesive matrix molecules; bone matrix; biomaterial;
D O I
10.1016/S0378-1097(99)00079-8
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Staphylococcus aureus is a frequent cause of orthopedic infections in humans. The bacterium expresses several adhesins that facilitate bacterial binding to the bone matrix and to bone implant biomaterials coated with host plasma constituents. The relevant S. aureus adhesins are termed microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) and specific MSCRAMMs are involved in bone and joint infections. (C) 1999 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:279 / 284
页数:6
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