Synthesis of wax esters and related trehalose esters from Mycobacterium avium and other mycobacteria

被引：6

作者：

Taher, Salam G. ^{[1
,3
]}

Al Dulayymi, Juma'a R. ^{[1
]}

Tima, H. Giresse ^{[2
]}

Ali, Hanan M. ^{[1
]}

Romano, Marta ^{[2
]}

Baird, Mark S. ^{[1
]}

机构：

[1] Bangor Univ, Sch Chem, Bangor LL57 2UW, Gwynedd, Wales

[2] Sci Inst Publ Hlth WIV ISP, OD Communicable & Infect Dis, Host Pathogen Interact Sci Serv Immunol, B-1180 Brussels, Belgium

[3] Koya Univ, Fac Sci & Hlth, Dept Chem, Koysinjaq, Iraq

来源：

TETRAHEDRON | 2016年 / 72卷 / 27-28期

基金：

欧盟地平线“2020”;

关键词：

Wax ester; Mycobacterium avium; TDM; TMM; Trehalose dimycolate; Trehalose monomycolate; Inflammation; MYCOLIC ACID PATTERNS; CORD-FACTOR; PULMONARY-DISEASE; RAPID SERODIAGNOSIS; ENZYME-IMMUNOASSAY; IGG ANTIBODY; THIN-LAYER; CELL-WALL; TUBERCULOSIS; COMPLEX;

D O I：

10.1016/j.tet.2016.05.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of mycobacterial mycolic acid related wax esters and of their trehalose di- and mono-esters is described. The trehalose dimycolates (TDMs) synthesised activated bone marrow derived dendritic cells (BMDCs) in vitro more strongly than trehalose dibehenate or the trehalose monomycolates (TMMs). The inflammatory effects were similar to those of TDM from either a synthetic keto- or methoxy-mycolic acid, but somewhat stronger than those of a TDM from an a-mycolic acid. In vivo, the effects of one wax ester TDM were similar to those of the methoxy-MA and a-mycolic acid TDMs and trehalose dibehenate. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：3863 / 3876

页数：14

共 50 条

[21] CLASSIFICATION OF MYCOBACTERIUM AVIUM AND RELATED OPPORTUNIST MYCOBACTERIA MET IN ENGLAND AND WALES
BIRN, KJ
SCHAEFER, WB
JENKINS, PA
SZULGA, T
MARKS, J
[J]. JOURNAL OF HYGIENE-CAMBRIDGE, 1967, 65 (04): : 575 - +
[22] Enzymatic synthesis of fatty acid esters of trehalose: Process optimization, characterization of the esters and evaluation of their bioactivities
Marathe, Sandesh J.
Shah, Nirali N.
Singhal, Rekha S.
[J]. BIOORGANIC CHEMISTRY, 2020, 94
[23] MICROBIOLOGICAL SYNTHESIS OF WAX ESTERS BY EUGLENA-GRACILIS
KORITALA, S
[J]. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1989, 66 (01) : 133 - 134
[24] WAX ESTERS FROM LARREA-DIVARICATA
SEIGLER, DS
JAKUPCAK, J
MABRY, TJ
[J]. PHYTOCHEMISTRY, 1974, 13 (06) : 983 - 986
[25] WAX ESTERS FROM MULLET EGG LIPIDS
SCHLENK, H
IYENGAR, BTR
[J]. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1966, 43 (03) : A102 - &
[26] MULTILOCUS ENZYME ELECTROPHORESIS ANALYSIS OF THE MYCOBACTERIUM-AVIUM COMPLEX AND OTHER MYCOBACTERIA
WASEM, CF
MCCARTHY, CM
MURRAY, LW
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1991, 29 (02) : 264 - 271
[27] Characterization of Mycobacterium avium complex related mycobacteria isolated from an African environment and patients with AIDS
Fonteyne, PA
Kunze, ZM
DeBeenhouwer, H
Dumonceau, JM
Dawson, DJ
McFadden, JJ
Portaels, F
[J]. TROPICAL MEDICINE & INTERNATIONAL HEALTH, 1997, 2 (02) : 200 - 207
[28] ENZYMATIC SYNTHESIS OF LONG CHAIN ALCOHOLS AND WAX ESTERS FROM FATTY ACIDS
KOLATTUK.PE
[J]. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1971, 48 (02) : A85 - &
[29] Factors influencing numbers of Mycobacterium avium, Mycobacterium intracellulare, and other mycobacteria in drinking water distribution systems
Falkinham, JO
Norton, CD
LeChevallier, MW
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2001, 67 (03) : 1225 - 1231
[30] THE VIRULENCE OF MYCOBACTERIUM-AVIUM AND RELATED MYCOBACTERIA FOR C57-MICE
MATTHEWS, PRJ
COLLINS, P
BUNCH, KJ
MCDIARMID, A
[J]. JOURNAL OF COMPARATIVE PATHOLOGY, 1982, 92 (03) : 387 - 392

← 1 2 3 4 5 →