Emergence of Vaccine-Derived Polioviruses during Ebola Virus Disease Outbreak, Guinea, 2014-2015

被引：9

作者：

Fernandez-Garcia, Maria Dolores ^{[1
]}

Majumdar, Manasi ^{[2
]}

Kebe, Ousmane ^{[1
]}

Fall, Aichatou D. ^{[1
]}

Kone, Moussa ^{[3
]}

Kande, Mouctar ^{[3
]}

Dabo, Moustapha ^{[4
]}

Sylla, Mohamed Salif ^{[4
]}

Sompare, Djenou ^{[4
]}

Howard, Wayne ^{[5
]}

Faye, Ousmane ^{[1
]}

Martin, Javier ^{[2
]}

Ndiaye, Kader ^{[1
]}

机构：

[1] Inst Pasteur, Dakar, Senegal

[2] Natl Inst Biol Stand & Controls, Potters Bar, Herts, England

[3] WHO, Conakry, Guinea

[4] Guinean Minist Hlth, Conakry, Guinea

[5] Natl Inst Communicable Dis, Johannesburg, South Africa

来源：

EMERGING INFECTIOUS DISEASES | 2018年 / 24卷 / 01期

关键词：

WORLDWIDE; UPDATE; IDENTIFICATION; POLIOMYELITIS; STRAIN; CHILD;

D O I：

10.3201/eid2401.171174

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

During the 2014-2015 outbreak of Ebola virus disease in Guinea, 13 type 2 circulating vaccine-derived polioviruses (cVDPVs) were isolated from 6 polio patients and 7 healthy contacts. To clarify the genetic properties of cVDPVs and their emergence, we combined epidemiologic and virologic data for polio cases in Guinea. Deviation of public health resources to the Ebola outbreak disrupted polio vaccination programs and surveillance activities, which fueled the spread of neurovirulent VDPVs in an area of low vaccination coverage and immunity. Genetic properties of cVDPVs were consistent with their capacity to cause paralytic disease in humans and capacity for sustained person-toperson transmission. Circulation ceased when coverage of oral polio vaccine increased. A polio outbreak in the context of the Ebola virus disease outbreak highlights the need to consider risks for polio emergence and spread during complex emergencies and urges awareness of the challenges in polio surveillance, vaccination, and diagnosis.

引用

下载

页码：65 / 74

页数：10

共 50 条

[31] Fears and Misperceptions of the Ebola Response System during the 2014-2015 Outbreak in Sierra Leone
Yamanis, Thespina
Nolan, Elisabeth
Shepler, Susan
PLOS NEGLECTED TROPICAL DISEASES, 2016, 10 (10):
[32] Evaluation of the performance of the National Tuberculosis Program of Liberia during the 2014-2015 Ebola outbreak
Desta, Kassaye Tekie
Kessely, Dedeh Barr
Daboi, Jerry G.
BMC PUBLIC HEALTH, 2019, 19 (01)
[33] Vaccine-Derived Polioviruses and Children with Primary Immunodeficiency, Iran, 1995-2014
Shaghaghi, Mohammadreza
Shahmahmoodi, Shohreh
Abolhassani, Hassan
Soleyman-jahi, Saeed
Parvaneh, Leila
Mahmoudi, Sussan
Chavoshzadeh, Zahra
Yazdani, Reza
Zahraei, Seyed Mohsen
Ebrahimi, Mohsen
Eslamian, Mohammad H.
Tabatabaie, Hamideh
Yousefi, Maryam
Kandelousi, Yaghoob M.
Oujaghlou, Aliasghar
Rezaei, Nima
Aghamohammadi, Asghar
EMERGING INFECTIOUS DISEASES, 2016, 22 (10) : 1712 - 1719
[34] Evolution and Spread of Ebola Virus in Liberia, 2014-2015
Ladner, Jason T.
Wiley, Michael R.
Mate, Suzanne
Dudas, Gytis
Prieto, Karla
Lovett, Sean
Nagle, Elyse R.
Beitzel, Brett
Gilbert, Merle L.
Fakoli, Lawrence
Diclaro, Joseph W., II
Schoepp, Randal J.
Fair, Joseph
Kuhn, Jens H.
Hensley, Lisa E.
Park, Daniel J.
Sabeti, Pardis C.
Rambaut, Andrew
Sanchez-Lockhart, Mariano
Bolay, Fatorma K.
Kugelman, Jeffrey R.
Palacios, Gustavo
CELL HOST & MICROBE, 2015, 18 (06) : 659 - 669
[35] Update on Vaccine-Derived Polioviruses - Worldwide, January 2015-May 2016
Jorba, Jaume
Diop, Ousmane M.
Iber, Jane
Sutter, Roland W.
Wassilak, Steven G.
Burns, Cara C.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT, 2016, 65 (30): : 763 - 769
[36] The impact of a prolonged ebola outbreak on measles elimination activities in Guinea, Liberia and Sierra Leone, 2014-2015
Masresha, Balcha Girma
Luce, Richard, Jr.
Weldegebriel, Goitom
Katsande, Reggis
Gasasira, Alex
Mihigo, Richard
PAN AFRICAN MEDICAL JOURNAL, 2020, 35 : 31 - 36
[37] Recombination between Polioviruses and Co-Circulating Coxsackie A Viruses: Role in the Emergence of Pathogenic Vaccine-Derived Polioviruses
Jegouic, Sophie
Joffret, Marie-Line
Blanchard, Claire
Riquet, Franck B.
Perret, Celine
Pelletier, Isabelle
Colbere-Garapin, Florence
Rakoto-Andrianarivelo, Mala
Delpeyroux, Francis
PLOS PATHOGENS, 2009, 5 (05)
[38] The Transmission Chain Analysis of 2014-2015 Ebola Virus Disease Outbreak in Koinadugu District, Sierra Leone: an Observational Study
Muoghalu, Ifeanyi-Stanley
Moses, Francis
Conteh, Ishata
Swaray, Patrick
Ajudua, Anthonia
Nordstrom, Anders
FRONTIERS IN PUBLIC HEALTH, 2017, 5
[39] Reporting in a health emergency: The roles of Sierra Leonean journalists during the 2014-2015 Ebola outbreak
Winters, Maike
Nordenstedt, Helena
Alvesson, Helle Molsted
PLOS NEGLECTED TROPICAL DISEASES, 2020, 14 (05): : 1 - 14
[40] Ebola virus disease in children during the 2014–2015 epidemic in Guinea: a nationwide cohort study
Mahamoud Sama Chérif
Nut Koonrungsesomboon
Diénaba Kassé
Sékou Ditinn Cissé
Saliou Bella Diallo
Fatoumata Chérif
Facély Camara
Alpha Koné
Eleonor Fundan Avenido
Mandiou Diakité
Mamadou Pathé Diallo
Edouard Le Gall
Mohamed Cissé
Juntra Karbwang
Kenji Hirayama
European Journal of Pediatrics, 2017, 176 : 791 - 796

← 1 2 3 4 5 →