Sodium chloride enhanced oligomerization of L-arginine

被引：8

作者：

Xin, L ^{[1
]}

Ma, YL ^{[1
]}

Liu, YN ^{[1
]}

Yan, Q ^{[1
]}

Wang, KJ ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Biophys, Beijing 100101, Peoples R China

来源：

BIOPOLYMERS | 2006年 / 81卷 / 01期

关键词：

L-arginine; oligoarginines; oligomerization; chloride ion; enhanced peptide formation;

D O I：

10.1002/bip.20354

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

NaCl significantly enhanced the longer oligoarginine formation in the oligomerization of L-arginine activated by N,N'-carbonyldiimidazole (CDI) in homogeneous aqueous solution. The optimal concentration of NaCl for the highest yield of longer oligoarginine formation is around l M. It is suggested that the weak interactions of Cl- with the positive-charged guanidinium group of the oligoarginines formed in the oligomerization of L-arginine are responsible for the enhancement by NaCl. (c) 2005 Wiley Periodicals, Inc.

引用

页码：1 / 7

页数：7

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