The antibacterial activity of plaunotol against Staphylococcus aureus isolated from the skin of patients with atopic dermatitis

被引：0

作者：

Matsumoto, Y

Hamashima, H

Masuda, K

Shiojima, K

Sasatsu, M ^{[1
]}

Arai, T

机构：

[1] Showa Coll Pharmaceut Sci, Dept Microbiol, Tokyo 1948543, Japan

[2] Showa Coll Pharmaceut Sci, Dept Phytochem, Tokyo 1948543, Japan

来源：

MICROBIOS | 1998年 / 96卷 / 385期

关键词：

plaunotol; antibacterial activity; atopic dermatitis; skin care; methicillin-resistant Staphylococcus aureus;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Plaunotol was tested for possible antibacterial activity against twenty strains of methicillin-resistant Staphylococcus aureus (MRSA) and fourteen strains of methicillin-sensitive S. aureus (MSSA) which had been isolated from the skin of patients with atopic dermatitis under growth-promoting conditions. Plaunotol was effective against all strains tested. The dose of plaunotol for 50% inhibition of growth (ID50) ranged from 2.5 to 16 mu g/ml for strains of MRSA and from 2.5 to 7.0 mu g/ml for those of MSSA. These results suggest that plaunotol may be useful in the prevention of infection by MRSA and in skin care for patients with atopic dermatitis.

引用

页码：149 / 155

页数：7

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