The antibacterial activity of plaunotol against Staphylococcus aureus isolated from the skin of patients with atopic dermatitis

被引：0
|
作者：
Matsumoto, Y
Hamashima, H
Masuda, K
Shiojima, K
Sasatsu, M [1 ]
Arai, T
机构：
[1] Showa Coll Pharmaceut Sci, Dept Microbiol, Tokyo 1948543, Japan
[2] Showa Coll Pharmaceut Sci, Dept Phytochem, Tokyo 1948543, Japan
来源：
MICROBIOS | 1998年 / 96卷 / 385期
关键词：
plaunotol; antibacterial activity; atopic dermatitis; skin care; methicillin-resistant Staphylococcus aureus;
D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Plaunotol was tested for possible antibacterial activity against twenty strains of methicillin-resistant Staphylococcus aureus (MRSA) and fourteen strains of methicillin-sensitive S. aureus (MSSA) which had been isolated from the skin of patients with atopic dermatitis under growth-promoting conditions. Plaunotol was effective against all strains tested. The dose of plaunotol for 50% inhibition of growth (ID50) ranged from 2.5 to 16 mu g/ml for strains of MRSA and from 2.5 to 7.0 mu g/ml for those of MSSA. These results suggest that plaunotol may be useful in the prevention of infection by MRSA and in skin care for patients with atopic dermatitis.
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页码：149 / 155
页数：7
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