From rigidity to conformational flexibility:: Macrocyclic templates derived from ansa-steroids

被引:15
|
作者
Bäurle, S [1 ]
Blume, T [1 ]
Mengel, A [1 ]
Parchmann, C [1 ]
Skuballa, W [1 ]
Bäsler, S [1 ]
Schäfer, M [1 ]
Sülzle, D [1 ]
Wrona-Metzinger, HP [1 ]
机构
[1] Schering AG, Res Ctr Europe, D-13342 Berlin, Germany
关键词
conformations; macrocycles; ring expansions; steroids;
D O I
10.1002/anie.200351385
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:3961 / 3964
页数:4
相关论文
共 50 条
  • [41] CONFORMATIONAL PROPERTIES OF SOME DIAMIDES DERIVED FROM PYRAZOLIDINE
    CACCAMESE, S
    FINOCCHIARO, P
    MARAVIGNA, P
    MONTAUDO, G
    GAZZETTA CHIMICA ITALIANA, 1977, 107 (7-8): : 415 - 420
  • [42] Structural alphabets derived from attractors in conformational space
    Alessandro Pandini
    Arianna Fornili
    Jens Kleinjung
    BMC Bioinformatics, 11
  • [43] Conformational analysis of peptides derived from the BRI gene
    Lelyveld, V
    El-Agnaf, O
    Siligardi, G
    Hussain, R
    Haris, PI
    Lee, M
    Austen, B
    SPECTROSCOPY-AN INTERNATIONAL JOURNAL, 2001, 15 (3-4): : 129 - 139
  • [44] Structural alphabets derived from attractors in conformational space
    Pandini, Alessandro
    Fornili, Arianna
    Kleinjung, Jens
    BMC BIOINFORMATICS, 2010, 11
  • [45] Difference contact maps: From what to why in the analysis of the conformational flexibility of proteins
    Iyer, Mallika
    Li, Zhanwen
    Jaroszewski, Lukasz
    Sedova, Mayya
    Godzik, Adam
    PLOS ONE, 2020, 15 (03):
  • [46] New evidence for conformational flexibility in cyclodextrins from vibrational Raman optical activity
    Bell, AF
    Hecht, L
    Barron, LD
    CHEMISTRY-A EUROPEAN JOURNAL, 1997, 3 (08) : 1292 - 1298
  • [47] Peroxy steroids derived from plant and fungi and their biological activities
    Vil, Vera A.
    Gloriozova, Tatyana A.
    Poroikov, Vladimir V.
    Terent'ev, Alexander O.
    Savidov, Nick
    Dembitsky, Valery M.
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 102 (18) : 7657 - 7667
  • [48] Role of conformational flexibility for enzymatic activity in NADH oxidase from Thermus thermophilus
    Zoldák, G
    Sut'ák, R
    Antalík, M
    Sprinzl, M
    Sedlák, E
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 2003, 270 (24): : 4887 - 4897
  • [49] CELTOS DOMAINS EXPOSED: FROM LIPID BINDING, CONFORMATIONAL FLEXIBILITY TO REGULATORY REGIONS
    Kumar, Hirdesh
    Jimah, John R.
    Ntumngia, Francis B.
    Barnes, Samantha
    Adams, John H.
    Schlesinger, Paul H.
    Tolia, Niraj H.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2019, 101 : 134 - 134
  • [50] Peroxy steroids derived from plant and fungi and their biological activities
    Vera A. Vil
    Tatyana A. Gloriozova
    Vladimir V. Poroikov
    Alexander O. Terent’ev
    Nick Savidov
    Valery M. Dembitsky
    Applied Microbiology and Biotechnology, 2018, 102 : 7657 - 7667