Cytokines of the IL-17 family in psoriasis

被引：10

作者：

Lauffer, Felix ^{[1
]}

Eyerich, Kilian ^{[1
]}

Boehncke, Wolf-Henning ^{[2
,3
]}

Asadullah, Khusru ^{[4
]}

Beissert, Stefan ^{[5
]}

Ghoreschi, Kamran ^{[6
]}

Schoen, Michael P. ^{[7
,8
]}

机构：

[1] Tech Univ Munich TUM, Dept Dermatol & Allergy Biederstein, Univ Hosp, Munich, Germany

[2] Univ Geneva, Univ Hosp Geneva, Div Dermatol & Venereol, Geneva, Switzerland

[3] Univ Geneva, Univ Hosp Geneva, Dept Pathol & Immunol, Geneva, Switzerland

[4] Dermatol Practice Potsdam, Potsdam, Germany

[5] Tech Univ Dresden, Carl Gustav Carus Univ Med Ctr, Dept Dermatol, Dresden, Germany

[6] Charite Univ Med Berlin, Dept Dermatol Venereol & Allergol, Berlin, Germany

[7] Gottingen Univ, Univ Med Ctr, Dept Dermatol Venereol & Allergol, Gottingen, Germany

[8] Lower Saxony Inst Occupat Dermatol, Gottingen, Germany

来源：

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT | 2020年

关键词：

S3; GUIDELINE; INFLAMMATION; NEUTROPHILS; CONTRIBUTES; VULGARIS; UPDATE;

D O I：

10.1111/ddg.14124

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Various immune cells and their messenger substances influence the development of psoriasis. Cytokines of the IL-17 family are of particular importance. In addition to IL-17A, which plays a central role in the pathogenesis of psoriasis, other subtypes of the IL-17 family also have a proinflammatory effect. This review provides an up-to-date overview of the immunopathogenesis of psoriasis with regard to the six IL-17 subtypes, in particular their physiological and pathogenic properties, as well as their significance for psoriasis therapy.

引用

页码：675 / 681

页数：7

共 50 条

[1] The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond
Brembilla, Nicolo Costantino
Senra, Luisa
Boehncke, Wolf-Henning
FRONTIERS IN IMMUNOLOGY, 2018, 9
[2] The Role of IL-17 Cytokines in Psoriasis
Mosca, Megan
Hong, Julie
Hadeler, Edward
Hakimi, Marwa
Liao, Wilson
Bhutani, Tina
IMMUNOTARGETS AND THERAPY, 2021, 10 : 409 - 418
[3] The IL-17 Family of Cytokines in Health and Disease
McGeachy, Mandy J.
Cua, Daniel J.
Gaffen, Sarah L.
IMMUNITY, 2019, 50 (04) : 892 - 906
[4] IL-17 family cytokines in inflammation and cancer
Dong, Chen
CYTOKINE, 2017, 100 : 19 - 20
[5] The IL-17 Family Cytokines in Immunity and Disease
Pappu, Rajita
Ramirez-Carrozzi, Vladimir
Ota, Naruhisa
Ouyang, Wenjun
Hu, Yan
JOURNAL OF CLINICAL IMMUNOLOGY, 2010, 30 (02) : 185 - 195
[6] Role of IL-17 family members in psoriasis
Towne, Jennifer E.
Zhang, Yu
Siegel, Lori A.
Symons, Antony
Budelsky, Alison L.
CYTOKINE, 2011, 56 (01) : 75 - 75
[7] IL-17 family: Cytokines, receptors and signaling
Gu, Chunfang
Wu, Ling
Li, Xiaoxia
CYTOKINE, 2013, 64 (02) : 477 - 485
[8] The IL-17 Family Cytokines in Immunity and Disease
Rajita Pappu
Vladimir Ramirez-Carrozzi
Naruhisa Ota
Wenjun Ouyang
Yan Hu
Journal of Clinical Immunology, 2010, 30 : 185 - 195
[9] Regulation of epithelial immunity by IL-17 family cytokines
Pappu, Rajita
Rutz, Sascha
Ouyang, Wenjun
TRENDS IN IMMUNOLOGY, 2012, 33 (07) : 343 - 349
[10] The role of IL-17 family cytokines in cardiac fibrosis
Huang, Liqing
FRONTIERS IN CARDIOVASCULAR MEDICINE, 2024, 11

← 1 2 3 4 5 →