Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles

被引:9
|
作者
Shirosaki, Yuki [1 ]
Okamoto, Kohei [2 ]
Hayakawa, Satoshi [2 ]
Osaka, Akiyoshi [2 ]
Asano, Takuji [3 ]
机构
[1] Kyushu Inst Technol, Frontier Res Acad Young Researchers, Wakamatsu Ku, Kitakyushu, Fukuoka 8080196, Japan
[2] Okayama Univ, Grad Sch Nat Sci & Technol, Kita Ku, Okayama 7008530, Japan
[3] Nikkiso Co Ltd, Shibuya Ku, Tokyo 1506022, Japan
关键词
SKULL DEFECTS; CRANIOPLASTY; CEMENT; CYTOCOMPATIBILITY; RECONSTRUCTION; MEMBRANE;
D O I
10.1155/2015/392940
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan and gamma-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition the porous hybrids maintained high porosity. The enzymatic degradation rate was low even after 6 months and the porous hybrids were very flexible and cut easily using surgical scissors.
引用
收藏
页数:6
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