Recent Advances in Magnetite Nanoparticle Functionalization for Nanomedicine

被引:82
|
作者
Popescu, Roxana Cristina [1 ,2 ]
Andronescu, Ecaterina [1 ]
Vasile, Bogdan Stefan [1 ]
机构
[1] Univ Politehn Bucuresti, Dept Sci & Oxide Mat & Nanomat, Natl Res Ctr Micro & Nanomat, Bucharest 060042, Romania
[2] Horia Hulubei Natl Inst Phys & Nucl Engn, Dept Life & Environm Phys, Magurele 077125, Romania
关键词
magnetite nanoparticles; Fe3O4; functionalization; surface modification; conjugation; nanomedicine; biocompatibility; clinical translation; IRON-OXIDE NANOPARTICLES; MESOPOROUS SILICA NANOPARTICLES; SUPERPARAMAGNETIC FE3O4 NANOPARTICLES; CHITOSAN-COATED FE3O4; BLOOD-BRAIN-BARRIER; GOLD NANOPARTICLES; IN-VITRO; SURFACE MODIFICATION; FOLIC-ACID; COPRECIPITATION SYNTHESIS;
D O I
10.3390/nano9121791
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Functionalization of nanomaterials can enhance and modulate their properties and behaviour, enabling characteristics suitable for medical applications. Magnetite (Fe3O4) nanoparticles are one of the most popular types of nanomaterials used in this field, and many technologies being already translated in clinical practice. This article makes a summary of the surface modification and functionalization approaches presented lately in the scientific literature for improving or modulating magnetite nanoparticles for their applications in nanomedicine.
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页数:31
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