Chitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings

被引：187

作者：

Mohandas, Annapoorna ^{[1
]}

Deepthi, S. ^{[1
]}

Biswas, Raja ^{[1
]}

Jayakumar, R. ^{[1
]}

机构：

[1] Amrita Vishwa Vidyapeetham, Amrita Inst Med Sci & Res Ctr, Ctr Nanosci & Mol Med, Kochi 682041, Kerala, India

来源：

BIOACTIVE MATERIALS | 2018年 / 3卷 / 03期

关键词：

Antimicrobial Chitosan nanocomposities; Silver; Zinc oxide; Gold; Copper; Wound healing; TITANIUM-DIOXIDE NANOPARTICLES; ZINC-OXIDE NANOPARTICLES; SILVER NANOPARTICLES; COPPER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; IN-VITRO; HEALING ACTIVITY; TOXICITY; GOLD; MECHANISMS;

D O I：

10.1016/j.bioactmat.2017.11.003

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Chitosan based nanocomposite scaffolds have attracted wider applications in medicine, in the area of drug delivery, tissue engineering and wound healing. Chitosan matrix incorporated with nanometallic components has immense potential in the area of wound dressings due to its antimicrobial properties. This review focuses on the different combinations of Chitosan metal nanocomposites such as Chitosan/nAg, Chitosan/nAu, Chitosan/nCu, Chitosan/nZnO and Chitosan/nTiO(2) towards enhancement of healing or infection control with special reference to the antimicrobial mechanism of action and toxicity. (c) 2017 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：267 / 277

页数：11

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