Androgen receptor gene mutation associated with complete androgen insensitivity syndrome and Sertoli cell adenoma

被引：6

作者：

Ko, HM

Chung, JH

Lee, JH

Jung, IS

Choi, IS

Juhng, SW

Choi, C

机构：

[1] Chonnam Natl Univ, Sch Med, Dept Pathol, Res Inst Med Sci, Kwangju 501746, South Korea

[2] Kwangju Vet Hosp, Dept Anat Pathol, Kwangju, South Korea

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY | 2001年 / 20卷 / 02期

关键词：

androgen receptor gene mutation; complete androgen insensitivity syndrome; Sertoli cell adenoma;

D O I：

10.1097/00004347-200104000-00014

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

We report a case of Sertoli cell adenoma in complete androgen insensitivity syndrome (CAIS) in a 22-year-old woman. Polymerase chain reaction-single strand conformation polymorphism and DNA sequencing revealed a single nucleotide substitution on exon 7 of the human androgen receptor (hAR) gene, resulting in a change of CGA (arginine) to CAA (glutamine) in codon 831.

引用

页码：196 / 199

页数：4

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