Galaxy: A platform for interactive large-scale genome analysis

被引：1473
|
作者：
Giardine, B
Riemer, C
Hardison, RC
Burhans, R
Elnitski, L
Shah, P
Zhang, Y
Blankenberg, D
Albert, I
Taylor, J
Miller, W
Kent, WJ
Nekrutenko, A [1 ]
机构：
[1] Penn State Univ, Huck Inst Life Sci, Ctr Comparat Genom & Bioinformat, University Pk, PA 16802 USA
[2] NHGRI, Bethesda, MD 20892 USA
[3] Univ Calif Santa Cruz, Dept Comp Sci & Engn, Santa Cruz, CA 95064 USA
来源：
GENOME RESEARCH | 2005年 / 15卷 / 10期
关键词：
D O I：
10.1101/gr.4086505
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe ail interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and Visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations Such as intersections, unions, and Subtractions; and links to other computational tools. Galaxy call be accessed at http://g2.bx.psu.edu.
引用
收藏
页码：1451 / 1455
页数：5
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