Microwave assisted synthesis of 3,5-diaryl-6-carbetboxy cyclohex-2-en-1-ones on solventless inorganic solid support and their antibacterial activities

被引：0
|
作者：
Roy, Ravindra S. [1 ]
Chundawat, Jagveer S. [1 ]
Dulawat, Shiv S. [1 ]
机构：
[1] BNPG Coll, Dept Chem, Udaipur 313001, Raj, India
来源：
AFINIDAD | 2011年 / 68卷 / 555期
关键词：
antibacterial activity; basic alumina; chalcones; cyclohexenone; microwave irradiation; CHALCONES; PYRIMIDINES;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A variety of 3,5-diaryl-6-carbethoxy cyclohex-2-en-1-ones derivatives (4a-g) were synthesized by the reaction of ethylacetoacetate with substituted chalcones in conventional (acetone & anhy. K2CO3) and microwave assisted solution phase (acetone & anhy. K2CO3) and dry media (basic Al2O3/piperidine). From the comparative study we have concluded that efficient dry media synthesis of 3,5 diaryl-6-carbethoxy cyclohex-2-en-1-ones under microwave irradiation can be carried out in domestic microwave oven with enhanced reaction rates and improved yields. The structure of compounds are supported by spectral and analytical data. The structure activity relationship of synthesized compounds have also been studied.
引用
收藏
页码：389 / 393
页数：5
相关论文
共 50 条
  • [41] Microwave-Assisted Synthesis of 2-(Arylidene)-1-thia-4-azaspiro[4.5]decan-3-ones and their Antibacterial, Antitubercular, and In Silico Screening
    Patel, Parth P.
    Patel, Navin B.
    Tople, Manesh S.
    Patel, Vatsal M.
    Rajani, Dhanji P.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2023, 33 (03) : 285 - 291
  • [42] Synthesis of 3′,4′-Diaryl-4′H-spiro[indoline-3,5′-[1′,2′,4′]-oxadiazol]-2-ones via DMAP-catalyzed Domino Reactions and Their Antibacterial Activity
    Shi, Guanghao
    He, Xinwei
    Shang, Yongjia
    Xiang, Liwei
    Yang, Cheng
    Han, Guang
    Du, Bing
    CHINESE JOURNAL OF CHEMISTRY, 2016, 34 (09) : 901 - 909
  • [43] COMPARATIVE STUDY OF CONVENTIONAL AND MICROWAVE-ASSISTED SYNTHESIS OF NOVEL 6-(ARYLIDENEAMINO)BENZO[d]OXAZOL-2(3H)-ONES WITH POTENTIAL ANTIBACTERIAL ACTIVITY
    Adjeroud, Yasmina
    Chabane, Hanane
    Liacha, Messaoud
    REVUE ROUMAINE DE CHIMIE, 2016, 61 (02) : 111 - +
  • [44] SYNTHESIS OF 1, 5-DIARYL-7-ETHOXY-1, 2, 4-TRIAZABICYCLO [3.2.0] HEPTA-2, 4, 6-TRIENES FROM 3-ARYLISOXAZOL-2-EN-5-ONES
    ASHOK, K
    DEVI, YU
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1988, 27 (03): : 229 - 232
  • [45] MICROWAVE ASSISTED SYNTHESIS OF 6-BENZOYL-5-METHYL-2-[(Z)-1-ARYL METHYLIDENE]-2,3-DIHYDROFURO [3',2' : 4,5] BENZO[b] FURAN-3-ONES AND THEIR ANTIBACTERIAL ACTIVITY
    Ashok, D.
    Sudershan, K.
    Khalilullah, M.
    HETEROCYCLIC LETTERS, 2011, 1 (04): : 359 - 364
  • [46] Microwave assisted solid support synthesis of novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazepines as potent antimicrobial agents
    Kidwai, M
    Sapra, P
    Misra, P
    Saxena, RK
    Singh, M
    BIOORGANIC & MEDICINAL CHEMISTRY, 2001, 9 (02) : 217 - 220
  • [47] Microwave-assisted synthesis and antibacterial activity of 1-[3-(3-fluorophenyl) [1,8]naphthyridn-2-yl]-3-(2-oxo-2H-chromenyl)-1H-4-pyrazolecarbaldehydes using solid support
    Mogilaiah, K.
    Prasad, R. Shiva
    Kumar, K. Shiva
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2010, 49 (10): : 1417 - 1421
  • [48] Microwave assisted one pot synthesis of (Z)-1,2-disubstituted 4-arylmethylene-2-imidazolin-5-ones using solid support under solvent free condition
    Tripathy, PK
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 14 (01) : 77 - 78
  • [49] Ultrasound- and microwave-assisted synthesis of (E)-1-aryl-3-[2-(piperidin-1-yl)quinolin-3-yl]prop-2-en-1-ones and (E)-1-aryl-3-[2-(pyrrolidin-1-yl)quinolin-3-yl]prop-2-en-1-ones, and their antimicrobial activity
    Ashok, D.
    Ganesh, Arram
    Lakshmi, B. Vijaya
    Ravi, S.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2014, 84 (06) : 1237 - 1242
  • [50] Ultrasound- and microwave-assisted synthesis of (E)-1-aryl-3-[2-(piperidin-1-yl)quinolin-3-yl]prop-2-en-1-ones and (E)-1-aryl-3-[2-(pyrrolidin-1-yl)quinolin-3-yl]prop-2-en-1-ones, and their antimicrobial activity
    D. Ashok
    Arram Ganesh
    B. Vijaya Lakshmi
    S. Ravi
    Russian Journal of General Chemistry, 2014, 84 : 1237 - 1242
12345