The pathology of sudden cardiac death in patients with ischemic heart disease - arrhythmology for anatomic pathologists

被引：21
|
作者：
Saffitz, JE [1 ]
机构：
[1] Washington Univ, Sch Med, Dept Pathol, St Louis, MO 63110 USA
[2] Washington Univ, Sch Med, Cardiovasc Res Ctr, St Louis, MO 63110 USA
来源：
CARDIOVASCULAR PATHOLOGY | 2005年 / 14卷 / 04期
基金：
美国国家卫生研究院;
关键词：
arrhythmia triggers; arrhythmia substrates; impulse conduction; intercellular coupling; current-load mismatch;
D O I：
10.1016/j.carpath.2005.04.005
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The goal of this review is to help anatomic pathologists interpret the significance of pathologic changes in the hearts of patients with coronary artery disease who died suddenly of spontaneous ventricular arrhythmias. Attention is focused on dynamic interactions between triggering events, such as acute ischemia, and stable anatomic substrates of arrhythmias, such as healed myocardial infarcts. A basic knowledge of arrhythmia mechanisms is necessary to understand the role of pathologic anatomy in the pathophysiology of sudden death. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码：195 / 203
页数：9
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