Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

被引:0
|
作者
Song, Weihua [1 ]
Zhang, Chaolin [2 ]
Hu, Yiguo [1 ]
Gkotzamanidou, Maria [3 ,4 ]
Shah, Parantu [1 ]
Shan, Weisong [5 ]
Yang, Guang [1 ]
Li, Yi [1 ]
Sperling, Adam [1 ]
Rashid, Naim [6 ]
Samur, Mehmet Kemal [1 ]
Amin, Samir B. [1 ]
Tai, Yu-Tzu [1 ]
Hideshima, Teru [1 ]
Parmigiani, Giovanni [6 ]
Magrangeas, Florence [7 ]
Minvielle, Stephane [7 ]
Avet-Loiseau, Herve [8 ]
Anderson, Kenneth C. [1 ]
Li, Cheng [6 ]
Munshi, Nikhil C. [9 ]
机构
[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Rockefeller Univ, New Yorki City, NY USA
[3] Harvard Univ, Sch Med, Dana Farber Canc Inst, LeBow Inst Myeloma Therapeut, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Myeloma Ctr,Dept Med Oncol, Boston, MA 02115 USA
[5] McGill Univ, Montreal, PQ, Canada
[6] Harvard Univ, Sch Publ Hlth, Dana Farber Canc Inst, Boston, MA 02115 USA
[7] CHU Nantes, F-44035 Nantes 01, France
[8] Univ Hosp Nantes, Nantes, France
[9] Harvard Univ, Sch Med, Dana Farber Canc Inst, Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
下载
收藏
页数:3
相关论文
共 50 条
  • [21] A vertebrate RNA-binding protein Fox-1 regulates tissue-specific splicing via the pentanucleotide GCAUG
    Jin, Y
    Suzuki, H
    Maegawa, S
    Endo, H
    Sugano, S
    Hashimoto, K
    Yasuda, K
    Inoue, K
    EMBO JOURNAL, 2003, 22 (04): : 905 - 912
  • [22] The Sam68 STAR RNA-Binding Protein Regulates mTOR Alternative Splicing during Adipogenesis
    Huot, Marc-Etienne
    Vogel, Gillian
    Zabarauskas, Amber
    Chau Tuan-Anh Ngo
    Coulombe-Huntington, Jasmin
    Majewski, Jacek
    Richard, Stephane
    MOLECULAR CELL, 2012, 46 (02) : 187 - 199
  • [23] Galectin-3 binding protein expression by tumor cells modulates the bone marrow microenvironment
    Fukaya, Yasushi
    Silverman, Ayaka
    Shimada, Hiroyuki
    Zandi, Ebrahim
    DeClerck, Yves
    CANCER RESEARCH, 2009, 69
  • [24] The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications
    Ogiya, Daisuke
    Liu, Jiye
    Ohguchi, Hiroto
    Kurata, Keiji
    Samur, Mehmet K.
    Tai, Yu-Tzu
    Adamia, Sophia
    Ando, Kiyoshi
    Hideshima, Teru
    Anderson, Kenneth C.
    BLOOD, 2020, 136 (20) : 2334 - 2345
  • [25] STAR family RNA-binding protein ASD-2 regulates developmental switching of mutually exclusive alternative splicing in vivo
    Ohno, Genta
    Hagiwara, Masatoshi
    Kuroyanagi, Hidehito
    GENES & DEVELOPMENT, 2008, 22 (03) : 360 - 374
  • [26] The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle
    Spletter, Maria L.
    Barz, Christiane
    Yeroslaviz, Assa
    Schoenbauer, Cornelia
    Ferreira, Irene R. S.
    Sarov, Mihail
    Gerlach, Daniel
    Stark, Alexander
    Habermann, Bianca H.
    Schnorrer, Frank
    EMBO REPORTS, 2015, 16 (02) : 178 - 191
  • [27] Natural antisense transcript TPM1-AS regulates the alternative splicing of tropomyosin I through an interaction with RNA-binding motif protein 4
    Huang, Guo-Wei
    Zhang, Ying-Li
    Liao, Lian-Di
    Li, En-Min
    Xu, Li-Yan
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2017, 90 : 59 - 67
  • [28] Transportin 2 Regulates Apoptosis through the RNA-binding Protein HuR
    von Roretz, Christopher
    Macri, Angelo M.
    Gallouzi, Imed-Eddine
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (29) : 25983 - 25991
  • [29] Maternal RNA binding protein with multiple splicing 2 (RBPMS2) is involved in mouse blastocyst formation through the bone morphogenetic protein pathway
    Zhou, Cheng
    Zheng, Lu
    Teng, Hui
    Yang, Ye
    Ma, Rujun
    Wang, Shuxian
    Yang, Yang
    Jing, Jun
    Li, Meiling
    Wu, Ronghua
    Chen, Li
    Yao, Bing
    REPRODUCTIVE BIOMEDICINE ONLINE, 2023, 47 (04)
  • [30] 17β-estradiol regulates the RNA-binding protein Noval, which then regulates the alternative splicing of estrogen receptor β in the aging female rat brain
    Shults, Cody L.
    Dingwall, Caitlin B.
    Kim, Chun K.
    Pinceti, Elena
    Rao, Yathindar S.
    Pak, Toni R.
    NEUROBIOLOGY OF AGING, 2018, 61 : 13 - 22