Amine N-oxides derived from alkaloids as chiral promoters in enantioselective Pauson-Khand reactions

被引：0
|
作者：
Derdau, V
Laschat, S
Jones, PG
机构：
[1] Tech Univ Braunschweig, Inst Organ Chem, D-38106 Braunschweig, Germany
[2] Tech Univ Braunschweig, Inst Anorgan & Analyt Chem, D-38106 Braunschweig, Germany
来源：
HETEROCYCLES | 1998年 / 48卷 / 07期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The novel indolizino[3,4-b]quinoline N-oxide (12) was prepared and characterized by X-Ray crystal structure determination. Compound (12) and sparteine N-oxides (8-10) were employed as chiral promoters in the Pauson-Khand cocyclization of various alkynes (1) with norbornene (4) to the bicyclic cyclopentenones (6) with enantioselectivities up to 33 %ee.
引用
收藏
页码：1445 / 1453
页数：9
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