First confirmed case of native polyomavirus BK nephropathy in a liver transplant recipient seven years post-transplant

被引:10
|
作者
Zeng, Yangmin [1 ]
Magil, Alex [2 ]
Hussaini, Trana [3 ]
Yeung, C. Kit [1 ]
Erb, Siegfried R. [4 ]
Marquez-Alazagara, Vladimir [4 ]
Yoshida, Eric M. [4 ]
机构
[1] Univ British Columbia, Div Nephrol, Vancouver, BC V5Z 1M9, Canada
[2] Univ British Columbia, Dept Pathol & Lab Med, Vancouver, BC V5Z 1M9, Canada
[3] Univ British Columbia, Fac Pharmaceut Sci, Vancouver, BC, Canada
[4] Univ British Columbia, Div Gastroenterol, Vancouver, BC V5Z 1M9, Canada
关键词
Liver; Transplantation; Polyomavirus; BK; Nephropathy; VIRUS-INFECTION; RISK-FACTORS; KIDNEY; JC; MORTALITY; OUTCOMES;
D O I
10.1016/S1665-2681(19)30812-9
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Renal dysfunction frequently occurs in liver transplant recipients and is associated with increased morbidity and mortality. BK virus is a human polyoma virus that reactivates during immunocompromised states and is a known cause of renal allograft dysfunction in renal transplant recipients. However, BK nephropathy of native kidneys is rare in non-renal transplant recipients. There is no published data linking BK virus and renal dysfunction in liver transplant recipients. We describe the first confirmed case of native polyomavirus BK nephropathy in a liver transplant recipient. BK nephropathy should be considered in the differential diagnosis of new renal failure in liver transplant recipients.
引用
收藏
页码:137 / 140
页数:4
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