Synthesis of benzimidazole derivatives and their antibacterial and antifungal activities

被引:0
|
作者
Bhatt, AK [1 ]
Karadiya, H [1 ]
Shah, PR [1 ]
Parmar, MP [1 ]
Patel, HD [1 ]
机构
[1] St Xavier Coll, Dept Chem, Ahmedabad 380009, Gujarat, India
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reaction of 2-phenyl 1-H benzimidazole 1 with p-aminobenzoic acid and aromatic aldehydes in ethanol furnishes 1-(alpha-p-carboxyphenyl-aminobenzyl) 2-phenyl Benzimidazoles 2, which on treatment with o-phenylene diamine in pyridine results in the formation of 1-(alpha-p-benzimidazolyl-aminobenzyl) 2-phenyl benzimidazoles 3. Antibacterial and antifungal activities of 3 were determined.
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页码:187 / 188
页数:2
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