LKB1 is required for normal glucose-signalling, but not insulin secretion, in pancreatic beta cells

被引:0
|
作者
Sayers, S. [1 ]
Hodson, D. J. [1 ]
Spegel, P. [2 ]
Mulder, H. [2 ]
Swisa, A. [3 ]
Dor, Y. [3 ]
Rutter, G. A. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, London SW7 2AZ, England
[2] Lund Univ, Ctr Diabet, S-22100 Lund, Sweden
[3] Hebrew Univ Jerusalem, Sch Med IMRC, IL-91905 Jerusalem, Israel
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
434
引用
收藏
页码:S215 / S216
页数:2
相关论文
共 50 条
  • [31] LKB1 in skeletal muscle plays important roles in insulin signaling and glucose homeostasis
    Koh, Ho-Jin
    Arnolds, David
    Hirshman, Michael
    Tran, Thien
    Fujii, Nobuharu
    Kahn, C. Ronald
    Goodyear, Laurie
    DIABETES, 2006, 55 : A12 - A12
  • [32] Pancreatic Peroxisomes Are Required for Physiological Regulation of Insulin Secretion and Maintenance of Normal Glucose Tolerance in Male Mice
    Burke, Susan
    Ghosh, Sujoy
    Burk, David
    Noland, Robert
    Collier, Jason
    DIABETES, 2023, 72
  • [33] Redox signalling is essential for efficient insulin secretion from beta cells upon glucose induction
    Holendova, B.
    Tauber, J.
    Jezek, P.
    Plecita-Hlavata, L.
    DIABETOLOGIA, 2019, 62 : S244 - S244
  • [34] Transcription factors involved in glucose-stimulated insulin secretion of pancreatic beta cells
    Shao, Shiying
    Fang, Zhong
    Yu, Xuefeng
    Zhang, Muxun
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 384 (04) : 401 - 404
  • [35] Heparan sulfate in pancreatic β-cells contributes to normal glucose homeostasis by regulating insulin secretion
    Matsuzawa, Takuro
    Yoshikawa, Takeo
    Iida, Tomomitsu
    Karpati, Aniko
    Kitano, Haruna
    Harada, Ryuichi
    Nakamura, Tadaho
    Sugawara, Akira
    Yamaguchi, Yu
    Yanai, Kazuhiko
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 499 (03) : 688 - 695
  • [36] Erratum to: Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E
    F. Fiory
    A. Lombardi
    C. Miele
    J. Giudicelli
    F. Beguinot
    E. Van Obberghen
    Diabetologia, 2012, 55 : 272 - 272
  • [37] The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing
    L. Luu
    F. F. Dai
    K. J. Prentice
    X. Huang
    A. B. Hardy
    J. B. Hansen
    Y. Liu
    J. W. Joseph
    M. B. Wheeler
    Diabetologia, 2013, 56 : 2010 - 2020
  • [38] The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing
    Luu, L.
    Dai, F. F.
    Prentice, K. J.
    Huang, X.
    Hardy, A. B.
    Hansen, J. B.
    Liu, Y.
    Joseph, J. W.
    Wheeler, M. B.
    DIABETOLOGIA, 2013, 56 (09) : 2010 - 2020
  • [39] Ghrelin signalling in β-cells regulates insulin secretion and blood glucose
    Yada, T.
    Damdindorj, B.
    Rita, R. S.
    Kurashina, T.
    Ando, A.
    Taguchi, M.
    Koizumi, M.
    Sone, H.
    Nakata, M.
    Kakei, M.
    Dezaki, K.
    DIABETES OBESITY & METABOLISM, 2014, 16 : 111 - 117
  • [40] LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice
    Men, Yuqin
    Zhang, Aizhen
    Li, Haixiang
    Zhang, Tingting
    Jin, Yecheng
    Li, Huashun
    Zhang, Jian
    Gao, Jiangang
    PLOS ONE, 2015, 10 (08):