Study of Nature of Paramagnetic Doublet in Mossbauer Spectra of Mice Liver Using External Magnetic Field

被引:1
|
作者
Gabbasov, R. R. [1 ]
Cherepanov, V. M. [1 ]
Chuev, M. A. [1 ,3 ]
Polikarpov, M. A. [1 ]
Nikitin, M. P. [2 ]
Deyev, S. M. [2 ]
Panchenko, V. Y. [1 ]
机构
[1] IV Kurchatov Atom Energy Inst, Natl Res Ctr, Moscow 123182, Russia
[2] RAS, Shemyakin Ovchinnikov Inst Bioorg Chem, Moscow, Russia
[3] RAS, Inst Phys & Technol, Moscow, Russia
来源
关键词
Mossbauer spectroscopy; magnetic nanoparticles; superparamagnetism; biodegradation; NANOPARTICLES; SPECTROSCOPY;
D O I
10.4028/www.scientific.net/SSP.190.729
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
A process of the biodegradation in vivo of a magnetic ferrofluid was investigated by Mossbauer spectroscopy. After the injection of the ferrofluid in a mice body an additional doublet was observed in the Mossbauer spectra of the mice liver. Further analysis showed that the doublet consists of two components with different magnetic properties. The components related both to the formation of non-magnetic ferritin-like proteins and superparamagnetic behavior of the injected nanoparticles. These components were Separated in an external magnetic field and the time evolution of each fraction was studied. The concentration of both of these fractions in the frame of multi-level relaxation model was estimated.
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页码:729 / +
页数:2
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