Multiple linear regression for protein secondary structure prediction

被引：17
|
作者：
Pan, XM [1 ]
机构：
[1] Acad Sinica, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China
来源：
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 2001年 / 43卷 / 03期
关键词：
protein folding; secondary structure prediction; multiple linear regression; consensus; jackknife; amino acid sequence;
D O I：
10.1002/prot.1036
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In the present work, a novel method was proposed for prediction of secondary structure. Over a database of 396 proteins (CB396) with a three-state-defining secondary structure, this method with jackknife procedure achieved an accuracy of 68.8% and SOV score of 71.4% using single sequence and an accuracy of 73.7% and SOV score of 77.3% using multiple sequence alignments. Combination of this method with DSC, PHD, PREDATOR, and NNSSP gives Q(3) = 76.2% and SOV = 79.8%. (C) 2001 Wiley-Liss, Inc.
引用
收藏
页码：256 / 259
页数：4
相关论文
共 50 条
  • [31] Multiple docking for protein structure prediction
    Inbar, Y
    Wolfson, HJ
    Nussinov, R
    INTERNATIONAL JOURNAL OF ROBOTICS RESEARCH, 2005, 24 (2-3): : 131 - 150
  • [32] Impact of protein dynamics on secondary structure prediction
    de Brevern, Alexandre G.
    BIOCHIMIE, 2020, 179 : 14 - 22
  • [33] PROTINFO: secondary and tertiary protein structure prediction
    Hung, LH
    Samudrala, R
    NUCLEIC ACIDS RESEARCH, 2003, 31 (13) : 3296 - 3299
  • [34] Protein secondary structure prediction with dihedral angles
    Wood, MJ
    Hirst, JD
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2005, 59 (03) : 476 - 481
  • [35] A Next Step in Protein Secondary Structure Prediction
    Liu, Hui
    Li, Yaohang
    Rata, Ionel
    Jakobsson, Eric
    BIOPHYSICAL JOURNAL, 2012, 102 (03) : 619A - 619A
  • [36] Combined approach to protein secondary structure prediction
    Amirova, S. R.
    Machavariani, M. A.
    Filatov, L., V
    Milchevsky, Ju. V.
    Esipova, N. G.
    Tumanyan, V. G.
    Proceedings of the Fourth International Conference on Bioinformatics of Genome Regulation and Structure, Vol 1, 2004, : 231 - 234
  • [37] An evaluation of protein secondary structure prediction algorithms
    Pappas, G
    Subramaniam, S
    TECHNIQUES IN PROTEIN CHEMISTRY VIII, 1997, 8 : 783 - 794
  • [38] REDEFINING THE GOALS OF PROTEIN SECONDARY STRUCTURE PREDICTION
    ROST, B
    SANDER, C
    SCHNEIDER, R
    JOURNAL OF MOLECULAR BIOLOGY, 1994, 235 (01) : 13 - 26
  • [39] Prediction of protein secondary structure at 80% accuracy
    Petersen, TN
    Lundegaard, C
    Nielsen, M
    Bohr, H
    Bohr, J
    Brunak, S
    Gippert, GP
    Lund, O
    PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2000, 41 (01) : 17 - 20
  • [40] HYBRID SYSTEM FOR PROTEIN SECONDARY STRUCTURE PREDICTION
    ZHANG, X
    MESIROV, JP
    WALTZ, DL
    JOURNAL OF MOLECULAR BIOLOGY, 1992, 225 (04) : 1049 - 1063
12345