The first separation and stereochemical determination of bis(α-hydroxyalkyl) phosphinic acids diastereoisomers

被引：26
|
作者：
Kaboudin, B [1 ]
Haghighat, H [1 ]
机构：
[1] IASBS, Dept Chem, Zanjan 451951159, Iran
来源：
TETRAHEDRON LETTERS | 2005年 / 46卷 / 46期
关键词：
phosphinic acids; stereochemistry; microwave; trimethyl orthoformate;
D O I：
10.1016/j.tetlet.2005.09.081
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A separation of bis(alpha-hydroxyalkyl) phosphinic acid diastereoisomers is described. A novel method for the determination stereochemistry of bis(alpha-hydroxyalkyl) phosphinic acid diastereoisomers has been developed. The stereochemistry of one diastereoisomer was confirmed after converting to the corresponding methyl ester using trimethyl orthoformate. (c) 2005 Published by Elsevier Ltd.
引用
收藏
页码：7955 / 7957
页数：3
相关论文
共 50 条
  • [31] STUDIES OF HYDROXY AMINO-ACIDS .2. SEPARATION OF DIASTEREOISOMERS OF HYDROXY AMINO-ACIDS
    ARIYOSHI, Y
    SATO, N
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1971, 44 (12) : 3435 - +
  • [32] Conformational investigations of bis(α-aminoalkyl)phosphinic acids and studies of the stability of their complexes with Cu(II)
    Latajka, R.
    Krezel, A.
    Mucha, A.
    Jewginski, M.
    Kafarski, P.
    JOURNAL OF MOLECULAR STRUCTURE, 2008, 877 (1-3) : 64 - 71
  • [33] SIMULTANEOUS ISOCRATIC HPLC SEPARATION OF THE DIASTEREOISOMERS OF CAFFEIC, FERULIC, AND ISOFERRULIC ACIDS AND RELATED COUMARINS
    BORGES, MFM
    ROLEIRA, FMF
    PINTO, MMM
    JOURNAL OF LIQUID CHROMATOGRAPHY, 1993, 16 (01): : 149 - 160
  • [34] Sensing Remote Chirality: Stereochemical Determination of β-, γ-, and δ-Chiral Carboxylic Acids
    Tanasova, Marina
    Anyika, Mercy
    Borhan, Babak
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (14) : 4274 - 4278
  • [35] PREPARATION OF N-(2-HYDROXYALKYL)-2-MORPHOLONES AND N,N-BIS(2-HYDROXYALKYL) AMINO ACIDS
    JANKOWSKI, K
    BERSE, C
    BULLETIN DE L ACADEMIE POLONAISE DES SCIENCES-SERIE DES SCIENCES CHIMIQUES, 1970, 18 (04): : 183 - +
  • [36] New heterocyclic mono- and bis(α-hydroxymethyl)phosphinic acids:: Synthesis and CuII binding abilities
    Olszewski, Tomasz Krzysztof
    Galezowska, Joanna
    Boduszek, Bogdan
    Kozlowski, Henryk
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 2007 (21) : 3539 - 3546
  • [37] Methylene-bis[(aminomethyl)phosphinic acids]: synthesis, acid-base and coordination properties
    David, Tomas
    Prochazkova, Sona
    Havlickova, Jana
    Kotek, Jan
    Kubicek, Vojtech
    Hermann, Petr
    Lukes, Ivan
    DALTON TRANSACTIONS, 2013, 42 (07) : 2414 - 2422
  • [38] SEPARATION OF LEAD(II) AND COPPER(II) BY PLASTICIZER MEMBRANES WITH SULPHUR ANALOGUS OF PHOSPHINIC ACIDS AS CARRIERS
    Kolodziejska, Marta
    Kozlowski, Cezary
    Ulewicz, Malgorzata
    PHYSICOCHEMICAL PROBLEMS OF MINERAL PROCESSING, 2013, 49 (01): : 267 - 276
  • [39] Phenoxyacetic acids:: separation and quantitative determination
    Cserháti, T
    Forgács, E
    JOURNAL OF CHROMATOGRAPHY B, 1998, 717 (1-2): : 157 - 178
  • [40] CHROMATOGRAPHIC SEPARATION AND DETERMINATION OF FRUIT ACIDS
    GOUDIE, AJ
    RIEMAN, W
    ANALYTICA CHIMICA ACTA, 1962, 26 (05) : 419 - &
12345