Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021

被引：11

作者：

Sander, Anna-Lena ^{[1
,2
,3
]}

Yadouleton, Anges ^{[4
,5
,6
]}

de Oliveira Filho, Edmilson F. ^{[1
,2
,3
]}

Tchibozo, Carine ^{[6
]}

Hounkanrin, Gildas ^{[6
]}

Badou, Yvette ^{[6
]}

Adewumi, Praise ^{[6
]}

Rene, Keke K. ^{[7
]}

Ange, Dossou ^{[7
]}

Sourakatou, Salifou ^{[7
]}

Sedjro, Eclou ^{[8
]}

Aissi, Melchior A. J. ^{[8
]}

Fidelia, Hinson ^{[8
]}

Djingarey, Mamoudou Harouna ^{[9
]}

Nagel, Michael ^{[10
]}

Jo, Wendy Karen ^{[1
,2
,3
]}

Moreira-Soto, Andres ^{[1
,2
,3
]}

Drosten, Christian ^{[1
,2
,3
,11
]}

Landt, Olfert ^{[12
]}

Corman, Victor Max ^{[1
,2
,3
,11
]}

Hounkpatin, Benjamin ^{[7
]}

Drexler, Jan Felix ^{[1
,2
,3
,11
]}

机构：

[1] Charite Univ Med Berlin, Berlin, Germany

[2] Free Univ Berlin, Berlin, Germany

[3] Humboldt Univ, Inst Virol, Berlin, Germany

[4] Ecole Normale Super Natitingou, Natitingou, Benin

[5] Univ Natl Sci Technol Ingn & Math UNSTIM, Cotonou, Benin

[6] Lab Fievres Hemorragigues Virales Benin, Cotonou, Benin

[7] Minist Hlth, Cotonou, Benin

[8] Conseil Natl Lutte VIH Sida TB Paludisme IST & Ep, Cotonou, Benin

[9] WHO, Hlth Emergencies Programme, Reg Off Africa, Brazzaville, Rep Congo

[10] Deutsch Gesell Int Zusammenarbeit, Bonn, Germany

[11] Charite Univ Med Berlin, German Ctr Infect Res DZIF, Berlin, Germany

[12] TIB Molbiol Syntheselab GmbH, Berlin, Germany

来源：

EMERGING INFECTIOUS DISEASES | 2021年 / 27卷 / 11期

基金：

比尔及梅琳达.盖茨基金会;

关键词：

D O I：

10.3201/eid2711.211353

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.

引用

页码：2899 / 2903

页数：5

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