Phosphorus halide free synthesis of 1,2,3,4-tetrahydroisophosphinoline 2-oxides

被引：3

作者：

Malysheva, Svetlana F. ^{[1
]}

Gusarova, Nina K. ^{[1
]}

Belogorlova, Natalia A. ^{[1
]}

Sutyrina, Anastasiya O. ^{[1
]}

Albanov, Alexander I. ^{[1
]}

Sukhov, Boris G. ^{[1
]}

Kuimov, Vladimir A. ^{[1
]}

Litvintsev, Yuriy I. ^{[1
]}

Trofimov, Boris A. ^{[1
]}

机构：

[1] Russian Acad Sci, Siberian Branch, AE Favorsky Irkutsk Inst Chem, Irkutsk 664033, Russia

来源：

MENDELEEV COMMUNICATIONS | 2018年 / 28卷 / 01期

关键词：

BETA-HYDROXYALKYLPHOSPHINE OXIDES; ORGANOPHOSPHORUS COMPOUNDS; CONVENIENT SYNTHESIS; PHOSPHINE; SECONDARY; CHALCOGENIDES; CYCLIZATION; ALDEHYDES;

D O I：

10.1016/j.mencom.2018.01.008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The herein developed phosphorus halide free synthesis of 1,2,3,4-tetrahydroisophosphinoline 2-oxides involves intramolecular heterocyclization of P,P-bis(2-arylethyl)-P-(alpha-hydroxybenzyl)phosphine oxides, available from styrenes, phosphine and aldehydes. The cyclization proceeds in the presence of FeCl3 at 80 degrees C, yield of the products is 53-60%.

引用

页码：29 / 30

页数：2

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