MicroRNA expression profile during the differentiation from 3T3-L1 cells into adipocyte

被引：0

作者：

Ling, H. Y. ^{[1
]}

Ou, H. S. ^{[1
]}

Lei, X. Y. ^{[1
]}

Zhu, B. Y. ^{[1
]}

Yin, W. D. ^{[1
]}

Liao, D. F. ^{[1
]}

机构：

[1] Univ S China, Inst Pharm & Pharmacol, Div Pharmacoprote, Hengyang, Peoples R China

来源：

RECENT ADVANCES IN CARDIOVASCULAR DISEASE: PROCEEDINGS OF THE 13TH WORLD CONGRESS HEART DISEASE | 2007年

关键词：

MicroRNA; adipocyte; 3T3-L1; differentiation; insulin signal;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study investigated the MicroRNA expression profile during the differentiation from 3T3-L1 preadipocytes into adipocytes by miRNAs microarray analysis. We found both 3T3-L1 preadipocytes and adipocytes express 331 miRNAs. In adipocyte, 26 miRNAs were upregulated and 2 miRNAs were downregulated compared to 3T3-L1 preadipocytes. Interestingly, we observed that the target genes of miR-21, miR-298, let-7e were associated with insulin signal pathway.

引用

页码：263 / 267

页数：5

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