MicroRNA expression profile during the differentiation from 3T3-L1 cells into adipocyte

被引：0
|
作者：
Ling, H. Y. [1 ]
Ou, H. S. [1 ]
Lei, X. Y. [1 ]
Zhu, B. Y. [1 ]
Yin, W. D. [1 ]
Liao, D. F. [1 ]
机构：
[1] Univ S China, Inst Pharm & Pharmacol, Div Pharmacoprote, Hengyang, Peoples R China
来源：
RECENT ADVANCES IN CARDIOVASCULAR DISEASE: PROCEEDINGS OF THE 13TH WORLD CONGRESS HEART DISEASE | 2007年
关键词：
MicroRNA; adipocyte; 3T3-L1; differentiation; insulin signal;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This study investigated the MicroRNA expression profile during the differentiation from 3T3-L1 preadipocytes into adipocytes by miRNAs microarray analysis. We found both 3T3-L1 preadipocytes and adipocytes express 331 miRNAs. In adipocyte, 26 miRNAs were upregulated and 2 miRNAs were downregulated compared to 3T3-L1 preadipocytes. Interestingly, we observed that the target genes of miR-21, miR-298, let-7e were associated with insulin signal pathway.
引用
收藏
页码：263 / 267
页数：5
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