Increased Expression of Immune Checkpoint Regulators LAG3 and CD70 in the Tumor Cells and Microenvironment in Immunodeficiency Associated Lymphoproliferative Disorders

被引：0
|
作者：
Sanchez, Sandra [1 ]
Cabrera, Luis Veloza [2 ,3 ]
Masaoutis, Christos [4 ]
Buehler, Marco [1 ]
Ribera, Inmaculada [5 ]
Sellares, Anna [1 ]
Arnaldos Perez, Cristina [1 ]
Castillo Giron, Carlos [1 ]
Frigola, Gerard [5 ]
Guerrero Pineda, Jose [6 ]
Lopez del Campo, Ricardo [1 ]
Juan, Manel [6 ]
Jares, Pedro [5 ]
Lekakis, Lazaros [7 ]
Ramos, Juan [7 ]
Balsas, Patricia [1 ]
Amador, Virginia [1 ]
Antoni Bombi, Josep [8 ]
Mira, Aurea [1 ]
Balague, Olga [6 ]
Martinez, Antonio [1 ]
机构：
[1] Univ Barcelona, Hosp Clin IDIBAPS, Barcelona, Spain
[2] CHU Vaudois, Lausanne, Switzerland
[3] Univ Lausanne, Lausanne, Switzerland
[4] Natl & Kapodistrian Univ Athens, Athens, Greece
[5] Hosp Clin Barcelona, Barcelona, Spain
[6] Univ Barcelona, Hosp Clin, Barcelona, Spain
[7] Univ Miami, Miller Sch Med, Sylvester Canc Ctr, Miami, FL 33136 USA
[8] Hosp Clin Barcelona, Barcelona, Spain
来源：
MODERN PATHOLOGY | 2022年 / 35卷 / SUPPL 2期
关键词：
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
942
引用
收藏
页码：1016 / 1017
页数：2
相关论文
共 39 条
  • [1] Increased Expression of Immune Checkpoint Regulators LAG3 and CD70 in the Tumor Cells and Microenvironment in Immunodeficiency Associated Lymphoproliferative Disorders
    Sanchez, Sandra
    Veloza Cabrera, Luis
    Masaoutis, Christos
    Buehler, Marco
    Ribera, Inmaculada
    Sellares, Anna
    Arnaldos Perez, Cristina
    Castillo Giron, Carlos
    Frigola, Gerard
    Guerrero Pineda, Jose
    Lopez del Campo, Ricardo
    Juan, Manel
    Jares, Pedro
    Lekakis, Lazaros
    Ramos, Juan
    Balsas, Patricia
    Amador, Virginia
    Antoni Bombi, Josep
    Mira, Aurea
    Balague, Olga
    Martinez, Antonio
    LABORATORY INVESTIGATION, 2022, 102 (SUPPL 1) : 1016 - 1017
  • [2] Strong Expression of the Immune Checkpoint Regulators LAG3 and Tim3 in Hodgkin Lymphoma
    el Halabi, Layal
    Adam, Julien
    Marty, Virginie
    Bosq, Jacques
    Lazarovici, Julien
    Danu, Alina
    Ribrag, Vincent
    Ghez, David
    BLOOD, 2016, 128 (22)
  • [3] Expression of immune checkpoint LAG3 is associated with high risk uveal melanoma
    Souri, Zahra
    Luyten, Gre
    Jager, Martine
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2021, 62 (08)
  • [4] Expression of Immune Checkpoint Regulators IDO, VISTA, LAG3, and TIM3 in Resected Pancreatic Ductal Adenocarcinoma
    Popp, Felix C.
    Capino, Ingracia
    Bartels, Joana
    Damanakis, Alexander I.
    Li, Jiahui
    Datta, Rabi R.
    Loeser, Heike
    Zhao, Yue
    Quaas, Alexander
    Lohneis, Philipp
    Bruns, Christiane J.
    CANCERS, 2021, 13 (11)
  • [5] LAG3 (LAG-3, CD223) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma
    Kluemper, Niklas
    Ralser, Damian J.
    Bawden, Emma Grace
    Landsberg, Jenny
    Zarbl, Romina
    Kristiansen, Glen
    Toma, Marieta
    Ritter, Manuel
    Hoelzel, Michael
    Ellinger, Joerg
    Dietrich, Dimo
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 (01)
  • [6] SOX11, CD70, and Treg cells configure the tumor-immune microenvironment of aggressive mantle cell lymphoma
    Balsas, Patricia
    Veloza, Luis
    Clot, Guillem
    Sureda-Gomez, Marta
    Rodriguez, Marta-Leonor
    Masaoutis, Christos
    Frigola, Gerard
    Navarro, Alba
    Bea, Silvia
    Nadeu, Ferran
    Gine, Eva
    Lopez-Guillermo, Armando
    Martinez, Antonio
    Ribera-Cortada, Inmaculada
    Engel, Pablo
    Quintanilla-Martinez, Leticia
    Klapper, Wolfram
    Campo, Elias
    Amador, Virginia
    BLOOD, 2021, 138 (22) : 2202 - 2215
  • [7] Expression of TIM3 (CD366) and LAG3 (CD223) in Colorectal Carcinoma-associated Inflammatory Infiltrate Suggest Novel Therapeutic Targets for Immune Checkpoint Blockade
    Drage, Michael
    Klapholz, Max
    Anderson, Ana C.
    Srivastava, Amitabh
    MODERN PATHOLOGY, 2018, 31 : 259 - 259
  • [8] Expression of TIM3 (CD366) and LAG3 (CD223) in Colorectal Carcinoma-associated Inflammatory Infiltrate Suggest Novel Therapeutic Targets for Immune Checkpoint Blockade
    Drage, Michael
    Klapholz, Max
    Anderson, Ana C.
    Srivastava, Amitabh
    LABORATORY INVESTIGATION, 2018, 98 : 259 - 259
  • [9] Tumor-Associated Inflammatory Cells and Immune Checkpoint Inhibitors Expression in Oral Potentially Malignant Disorders
    Flores, Andres
    Aly, F. Zahra
    Steward-Tharp, Scott
    LABORATORY INVESTIGATION, 2023, 103 (03) : S1037 - S1038
  • [10] Class I HDAC inhibitor domatinostat beneficially affects phenotype and functionality of T cells in the tumor microenvironment, and synergizes with PD-1/LAG3 checkpoint blockade
    Hamm, Svetlana
    Parnitzke, Ulrike
    Bartz, Rene
    Hermann, Frank
    JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 17
1234