Periodate oxidized invertase was immobilized by adsorption on sepiolite. The obtained immobilized enzyme was more resistant to washing out by concentrated salt solution. and had an eight times higher half-life at 60 degreesC than adsorbed native invertase. In packed bed reactor 50%, conversion of 500 g/dm(3) sucrose at 40 degreesC and a flow rate of 1 bv/h was achieved. The specific productivity of the immobilized invertase was 0.187 kg/dm(3)/h.