Discovery of novel CDC7 inhibitors that disrupt cell cycle dynamics and show anti-proliferative effects in cancer cells.

被引：0

作者：

Tsvetkov, Lyuben ^{[1
]}

Levinson, Adam ^{[1
]}

Huang, Xianhai ^{[1
]}

Mondal, Sayan ^{[1
]}

Bell, Jeff ^{[1
]}

Tang, Lin ^{[2
]}

Pelletier, Robert ^{[1
]}

Dingley, Karen ^{[1
]}

Boyles, Nick ^{[3
]}

Elk, Jackson Chief ^{[3
]}

Frye, Leah ^{[3
]}

Futran, Alan ^{[1
]}

Ghanakota, Phani ^{[1
]}

Greenwood, Jeremy ^{[1
]}

Lai, George ^{[1
]}

Silvergleid, Sarah ^{[1
]}

Yin, Wu ^{[1
]}

Wright, Hamish ^{[1
]}

Akinsanya, Karen ^{[1
]}

Tang, Wayne ^{[1
]}

Jensen, Kristian ^{[1
]}

机构：

[1] Schrodinger, New York, NY USA

[2] Schrodinger, San Diego, CA USA

[3] Schrodinger, Portland, OR USA

来源：

CANCER RESEARCH | 2021年 / 81卷 / 13期

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

1277

引用

页数：1

共 50 条

[41] A novel kinase inhibitor with multi-targeted anti-proliferative activity inducing apoptosis and cell cycle dysregulation in human leukemia cells
Mei, J
Tuman, R
Lu, H
Sechler, J
Baker, J
Garrabrant, T
Tominovich, R
DeVine, A
Ho, C
Ludovici, D
Strobel, E
Galemmo, R
Johnson, D
ANNALS OF ONCOLOGY, 2005, 16 : 43 - 43
[42] ANTI-PROLIFERATIVE EFFECTS OF 20(S)GINSENOSIDE Rh3 ON MCF-7 HUMAN BREAST CANCER CELLS
Tian, Jingwei
Fu, Fenghua
Geng, Meiyu
ANTICANCER RESEARCH, 2004, 24 (5D) : 3653 - 3653
[43] Anti-proliferative effect of estrogen in breast cancer cells that re-express ERα is mediated by aberrant regulation of cell cycle genes
Moggs, JG
Murphy, TC
Lim, FL
Moore, DJ
Stuckey, R
Antrobus, K
Kimber, I
Orphanides, G
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2005, 34 (02) : 535 - 551
[44] Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E2-independent mechanisms
Deasy, B. M.
O'Sullivan-Coyne, G.
O'Donovan, T. R.
Mckenna, S. L.
O'Sullivan, G. C.
CANCER LETTERS, 2007, 256 (02) : 246 - 258
[45] Anti-proliferative effects of lichen-derived lipoxygenase inhibitors on twelve human cancer cell lines of different tissue origin in vitro
Haraldsdóttir, S
Gudlaugsdóttir, E
Ingólfsdóttir, K
Ögmundsdóttir, HM
PLANTA MEDICA, 2004, 70 (11) : 1098 - 1100
[46] Novel curcumin analogue IHCH exhibits potent anti-proliferative effects by inducing autophagy in A549 lung cancer cells
Zhou, Guang-Zhou
Xu, Su-Li
Sun, Gang-Chun
Chen, Xiao-Bing
MOLECULAR MEDICINE REPORTS, 2014, 10 (01) : 441 - 446
[47] Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells
Cervello, Melchiorre
Bachvarov, Dimcho
Lampiasi, Nadia
Cusimano, Antonella
Azzolina, Antonina
McCubrey, James A.
Montalto, Giuseppe
PLOS ONE, 2013, 8 (06):
[48] Novel combination of salinomycin and resveratrol synergistically enhances the anti-proliferative and pro-apoptotic effects on human breast cancer cells
Jayant Dewangan
Divya Tandon
Sonal Srivastava
Ajeet Kumar Verma
Ashok Yapuri
Srikanta Kumar Rath
Apoptosis, 2017, 22 : 1246 - 1259
[49] Novel combination of salinomycin and resveratrol synergistically enhances the anti-proliferative and pro-apoptotic effects on human breast cancer cells
Dewangan, Jayant
Tandon, Divya
Srivastava, Sonal
Verma, Ajeet Kumar
Yapuri, Ashok
Rath, Srikanta Kumar
APOPTOSIS, 2017, 22 (10) : 1246 - 1259
[50] Synthesis of novel benzothiazole amides: Evaluation of PPAR activity and anti-proliferative effects in paraganglioma, pancreatic and colorectal cancer cell lines
Ammazzalorso, Alessandra
De Lellis, Laura
Florio, Rosalba
Laghezza, Antonio
De Filippis, Barbara
Fantacuzzi, Marialuigia
Giampietro, Letizia
Maccallini, Cristina
Tortorella, Paolo
Veschi, Serena
Loiodice, Fulvio
Cama, Alessandro
Amoroso, Rosa
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 29 (16) : 2302 - 2306

← 1 2 3 4 5 →