共 50 条
Effect of erythropoietin administration on the expression of brain-derived neurotrophic factor, stromal cell-derived Factor-1, and neuron-specific enolase in traumatic brain injury: A literature review
被引:6
|作者:
Said, Muhammad Fadli
[1
]
Islam, Andi Asadul
[1
]
Massi, Muhammad Nasrum
[2
]
Prihantono
[3
]
机构:
[1] Hasanuddin Univ, Dept Neurosurg, Fac Med, Makassar, South Sulawesi, Indonesia
[2] Hasanuddin Univ, Dept Microbiol, Fac Med, Makassar, South Sulawesi, Indonesia
[3] Hasanuddin Univ, Dept Surg, Fac Med, Makassar, South Sulawesi, Indonesia
来源:
关键词:
Traumatic brain injury;
Erythropoietin;
SDF-1;
Neuroprotection;
BDNF;
NSE;
RECOMBINANT-HUMAN-ERYTHROPOIETIN;
IMPROVES FUNCTIONAL RECOVERY;
DOUBLE-BLIND;
RECEPTORS;
APOPTOSIS;
P75(NTR);
MODEL;
RATS;
TRKB;
D O I:
10.1016/j.amsu.2021.102666
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Traumatic brain injury (TBI) is a major cause of death and lifelong disability around the world that predominantly affects young and middle-aged people. Erythropoietin (EPO) is a promising therapeutic agent for a variety of neurological injuries including TBI due to its neuroprotective effects. Here we review the impact of exogenous erythropoietin administration on the expression of brain-derived neurotrophic factor (BDNF), stromal cell derived factor-1 (SDF-1), and neuron-specific enolase (NSE) levels in cerebrospinal fluid after TBI as biomarkers for neuron regeneration and survival to predict TBI outcome.
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页数:4
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