Anti-Inflammatory and Immunomodulatory Activities of Stem Cells

被引:43
|
作者
Peroni, John F. [1 ]
Borjesson, Dori L. [2 ]
机构
[1] Univ Georgia, Coll Vet Med, Dept Large Anim Med, Athens, GA 30602 USA
[2] Univ Calif Davis, Sch Vet Med, Dept Pathol Microbiol & Immunol, Davis, CA 95616 USA
关键词
Equine; Stem cell; Mesenchymal stem cell; Regenerative medicine; Immunomodulation; Inflammation; UMBILICAL-CORD BLOOD; BONE-MARROW; INDOLEAMINE 2,3-DIOXYGENASE; LYMPHOCYTE-PROLIFERATION; T-LYMPHOCYTE; PERIPHERAL-BLOOD; DENDRITIC CELLS; ADIPOSE-TISSUE; IFN-GAMMA; IN-VITRO;
D O I
10.1016/j.cveq.2011.06.003
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The recent interest in equine stem cell biology and the rapid increase in experimental data highlight the growing attention that this topic has been receiving over the past few years. Within the field of stem cell biology, the relevance of immunobiology is of particular intrigue. It appears that optimal and effective stem cell therapy for equine patients will require a thorough analysis of the immune properties of stem cells as well as their response to immune mediators. The main goal of this review is to discuss the biology of adult mesenchymal stem cells in the context of immunology.
引用
收藏
页码:351 / +
页数:13
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