The cognitive neuropsychiatry of Tourette syndrome

被引:15
|
作者
Cavanna, Andrea E. [1 ,2 ,3 ,4 ,5 ]
Ganos, Christos [6 ]
Hartmann, Andreas [7 ,8 ,9 ]
Martino, Davide [10 ,11 ]
Pringsheim, Tamara [12 ]
Seri, Stefano [5 ]
机构
[1] BSMHFT, Dept Neuropsychiat, Birmingham, W Midlands, England
[2] Univ Birmingham, Birmingham, W Midlands, England
[3] Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London, England
[4] UCL, London, England
[5] Aston Univ, Aston Brain Ctr, Sch Life & Hlth Sci, Birmingham, W Midlands, England
[6] Univ Med Berlin, Dept Neurol, Charite, Berlin, Germany
[7] Grp Hosp Pitie Salpetriere, French Reference Ctr Gilles Tourette Syndrome, Paris, France
[8] Sorbonne Univ, UPMC Univ Paris 06, CNRS, UMR 7225,ICM,UMR S 1127, Paris, France
[9] Grp Hosp Pitie Salpetriere, AP HP, Dept Neurol, Paris, France
[10] Univ Calgary, Cumming Sch Med, Dept Clin Neurosci, Calgary, AB, Canada
[11] Hotchkiss Brain Inst, Calgary, AB, Canada
[12] Univ Calgary, Dept Clin Neurosci Psychiat Pediat & Community Hl, Calgary, AB, Canada
关键词
Tourette syndrome; tics; cognitive neuropsychiatry; perception-action binding; social decision-making; premonitory urges; behaviour; obsessive-compulsive disorder; attention-deficit and hyperactivity disorder; health-related quality of life; OBSESSIVE-COMPULSIVE DISORDER; SOCIAL DECISION-MAKING; QUALITY-OF-LIFE; PSYCHIATRIC-DISORDERS; INHIBITORY CONTROL; BASAL GANGLIA; TIC DISORDERS; PREVALENCE; ADULTS; POPULATION;
D O I
10.1080/13546805.2020.1760812
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Introduction: Converging evidence from both clinical and experimental studies has shown that Tourette syndrome (TS) is not a unitary condition, but a cluster of multiple phenotypes, which encompass both tics and specific behavioural and cognitive symptoms (mainly attention-deficit and hyperactivity disorder and obsessive-compulsive disorder). Methods: We conducted a narrative review of the recent literature on the cognitive neuropsychiatry of TS. Results: Although clinical research has shown that TS is not associated with cognitive deficits per se, the findings of recent studies have suggested the presence of subtle alterations in specific cognitive functions. A promising line of research on imitative behaviour could provide a common background for the alterations in executive control and social cognition observed in TS. Two different (but not mutually exclusive) neurocognitive theories have recently suggested that TS could originate from altered perception-action binding and social decision-making dysfunction, respectively. Conclusions: Since the presence of behavioural comorbidities influences individualised treatment approaches, it is likely that a more precise characterisation of TS phenotypes, including cognitive aspects, will result in improved levels of care for patients with tic disorders.
引用
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页码:254 / 268
页数:15
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