High-throughput synthesis and characterization of next-generation lipid nanoparticles for enhanced in vivo performance

被引:2
|
作者
Nelson, Bryant C. [1 ]
Borgos, Sven Even [2 ]
机构
[1] NIST, Mat Measurement Lab, Gaithersburg, MD 20899 USA
[2] SINTEF Ind, Dept Biotechnol & Nanomed, NO-7465 Trondheim, Norway
关键词
antisense oligonucleotides; combinatorial synthesis; DNA barcodes; drug delivery; high-throughput screening; lipid nanoparticles; mRNA barcodes; mRNA-LNP; nanomedicines; nucleic acid delivery; MESSENGER-RNA; DELIVERY;
D O I
10.2217/nnm-2022-0024
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:573 / 576
页数:4
相关论文
共 50 条
  • [31] High-throughput and Cost-effective Chicken Genotyping Using Next-Generation Sequencing
    Fábio Pértille
    Carlos Guerrero-Bosagna
    Vinicius Henrique da Silva
    Clarissa Boschiero
    José de Ribamar da Silva Nunes
    Mônica Corrêa Ledur
    Per Jensen
    Luiz Lehmann Coutinho
    Scientific Reports, 6
  • [32] Next-Generation qPCR for the High-Throughput Measurement of Gene Expression in Multiple Leukocyte Subsets
    Adamski, Mateusz G.
    Li, Yan
    Wagner, Erin
    Yu, Hua
    Seales-Bailey, Chloe
    Soper, Steven A.
    Murphy, Michael
    Baird, Alison E.
    JOURNAL OF BIOMOLECULAR SCREENING, 2013, 18 (09) : 1008 - 1017
  • [33] HybSelect: high-throughput access to genomic regions of interest for targeted next-generation sequencing
    Daniel Summerer
    Nature Methods, 2009, 6 (9) : v - vi
  • [34] Evaluation of High-Throughput Next-Generation Sequencing Applied in the Pathogenic Diagnosis of Bloodstream Infections
    Fang, Yuan
    Wang, Tao
    Jin, Li
    Li, Zhi-Tao
    Zhang, Jian-Qing
    Yang, Yang
    Zeng, Zhong
    Huang, Han Fei
    JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2020, 13 (10) : 1 - 5
  • [35] High-throughput and Cost-effective Chicken Genotyping Using Next-Generation Sequencing
    Pertille, Fabio
    Guerrero-Bosagna, Carlos
    da Silva, Vinicius Henrique
    Boschiero, Clarissa
    da Silva Nunes, Jose de Ribamar
    Ledur, Monica Correa
    Jensen, Per
    Coutinho, Luiz Lehmann
    SCIENTIFIC REPORTS, 2016, 6
  • [36] Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles
    Fan, Yuchen
    Yen, Chun-Wan
    Lin, Hsiu-Chao
    Hou, Weijia
    Estevez, Alberto
    Sarode, Apoorva
    Goyon, Alexandre
    Bian, Juan
    Lin, Jessica
    Koenig, Stefan G.
    Leung, Dennis
    Nagapudi, Karthik
    Zhang, Kelly
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 599
  • [37] HIGH-RESOLUTION CHARACTERIZATION OF ALLELIC AND HAPLOTYPIC HLA FREQUENCIES DISTRIBUTION IN A SPANISH POPULATION USING HIGH-THROUGHPUT NEXT-GENERATION SEQUENCING
    Montero-Martin, Gonzalo
    Creary, Lisa E.
    Mallempati, Kalyan
    Gangavarapu, Sridevi
    Vayntrub, Tamara
    Planelles, Dolores
    Vilches, Carlos
    Luis Caro, Jose
    Jose Herrero-Mata, Maria
    Sanchez-Gordo, Francisco
    Francisca Gonzalez-Escribano, Maria
    Muro, Manuel
    Moya-Quiles, Maria R.
    Gonzalez-Fernandez, Rafael
    Sanchez-Garcia, Florentino
    Gonzalo Ocejo-Vinyals, J.
    Balas, Antonio
    Luis Vicario, Jose
    Marin, Luis
    Fernandez-Vina, Marcelo A.
    HLA, 2018, 91 (05) : 424 - 425
  • [38] High-throughput targeted genotyping using next-generation sequencing applied in Coffea canephora breeding
    Alkimim, Emilly Ruas
    Caixeta, Eveline Teixeira
    Sousa, Tiago Vieira
    da Silva, Felipe Lopes
    Sakiyama, Ney Sussumu
    Zambolim, Laercio
    EUPHYTICA, 2018, 214 (03)
  • [39] A high-throughput belowground plant diversity assay using next-generation sequencing of the trnL intron
    E. G. Lamb
    T. Winsley
    C. L. Piper
    S. A. Freidrich
    S. D. Siciliano
    Plant and Soil, 2016, 404 : 361 - 372
  • [40] Next-Generation High-Throughput Sequencing to Evaluate Bacterial Communities in Freshwater Ecosystem in Hydroelectric Reservoirs
    Rojas, Martha Virginia R.
    Alonso, Diego Peres
    Dropa, Milena
    Razzolini, Maria Tereza P.
    de Carvalho, Dario Pires
    Nabas Ribeiro, Kaio Augusto
    Ribolla, Paulo Eduardo M.
    Sallum, Maria Anice M.
    MICROORGANISMS, 2022, 10 (07)