Cryptococcus gattii meningoencephalitis in an HIV-negative patient from the Peruvian Andes

被引：4

作者：

Gutierrez, Ericson L. ^{[2
]}

Valqui, Willi ^{[2
,4
]}

Vilchez, Luis ^{[4
]}

Evangelista, Lourdes ^{[5
]}

Crispin, Sarita ^{[5
]}

Tello, Mercedes ^{[2
]}

Navincopa, Marcos ^{[3
]}

Bejar, Vilma ^{[3
]}

Gonzales, Jose ^{[5
]}

Ortega-Loayza, Alex G. ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Dept Internal Med, Richmond, VA 23298 USA

[2] Natl Univ San Marcos, Inst Clin Res, Lima, Peru

[3] Natl Univ San Marcos, Inst Trop Med, Lima, Peru

[4] Dos de Mayo Natl Hosp, Dept Med, Lima, Peru

[5] Natl Univ San Marcos, Sch Med, Lima, Peru

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2010年 / 43卷 / 04期

关键词：

Cryptococcus gatti; Meningoencephalitis; CENTRAL-NERVOUS-SYSTEM;

D O I：

10.1590/S0037-86822010000400029

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

We report a case of an immunocompetent Peruvian patient from the Andes with a one-month history of meningoencephalitis. Cryptococcus gattii was identified from a cerebrospinal fluid culture through assimilation of D-proline and D-tryptophan as the single nitrogen source. Initially, the patient received intravenous antifungal therapy with amphotericin B. The patient was discharged 29 days after hospitalization and continued with oral fluconazole treatment for ten weeks. During this period, the patient showed clinical improvement with slight right-side residual weakness. Through this case report, we confirm the existence of this microorganism as an infectious agent in Peru.

引用

页码：469 / 471

页数：3

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