Eliminating the "Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance" Category From the Bethesda System for Reporting Thyroid Cytopathology

被引：58
|
作者：
Singh, Remmi S. [1 ]
Wang, Helen H. [1 ]
机构：
[1] Beth Israel Deaconess Med Ctr, Dept Pathol, Boston, MA 02215 USA
来源：
AMERICAN JOURNAL OF CLINICAL PATHOLOGY | 2011年 / 136卷 / 06期
关键词：
Atypia of undetermined significance; Follicular lesion of undetermined significance; Bethesda System for Reporting Thyroid Cytopathology; Thyroid lesions; Cytology; FINE-NEEDLE-ASPIRATION; HURTHLE CELL-CARCINOMA; MALIGNANCY; MANAGEMENT; DIAGNOSIS; CYTOLOGY; RISK;
D O I：
10.1309/AJCPIX52MBOKTICP
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
The "Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance (A US/FLUS)" category in the Bethesda System for Reporting Thyroid Cytology is heterogeneous and includes both specimens with borderline cellularity/compromised quality and those with genuine atypia. We have used a reporting scheme that is similar to the Bethesda System but does not include an AUS/FLUS category. We retrospectively reviewed all reports on thyroid FNA and thyroidectomy specimens submitted to the Beth Israel Deaconess Medical Center from January 2006 to December 2008. The positive predictive values for various categories and subcategories in this scheme demonstrate that the AUS/FLUS category can be eliminated to provide information for the most appropriate management of patients with thyroid nodules.
引用
收藏
页码：896 / 902
页数：7
相关论文
共 50 条
  • [21] The Correlation of Age with Prognosis of Atypia of Undetermined Significance and Follicular Lesion of Undetermined Significance in Thyroid Nodules
    Kaliszewski, Krzysztof
    Diakowska, Dorota
    Rzeszutko, Marta
    Wojtczak, Beata
    Rudnicki, Jerzy
    [J]. CANCER MANAGEMENT AND RESEARCH, 2021, 13 : 3101 - 3111
  • [22] Reproducibility of atypia of undetermined significance/follicular lesion of undetermined significance category using the bethesda system for reporting thyroid cytology when reviewing slides from different institutions: A study of interobserver variability among cytopathologists
    Padmanabhan, Vijayalakshmi
    Marshall, Carrie B.
    Barkan, Guliz Akdas
    Ghofrani, Mohiedean
    Laser, Alice
    Ocal, Idris Tolgay
    Sturgis, Charles David
    Souers, Rhona
    Kurtycz, Daniel F. I.
    [J]. DIAGNOSTIC CYTOPATHOLOGY, 2017, 45 (05) : 399 - 405
  • [23] Malignancy Rate of Thyroid Nodules Defined as Follicular Lesion of Undetermined Significance and Atypia of Undetermined Significance in Thyroid Cytopathology and Its Relation with Ultrasonographic Features
    Neslihan Çuhaci
    Dilek Arpaci
    Rıfki Üçler
    Aylin Kilic Yazgan
    Gülten Kıyak
    Samet Yalçin
    Pamir Eren Ersoy
    Gülnür Güler
    Reyhan Ersoy
    Bekir Çakir
    [J]. Endocrine Pathology, 2014, 25 : 248 - 256
  • [24] Thyroid Atypia/Follicular Lesion of Undetermined Significance: Attitudes towards the Diagnosis of Bethesda System III Nodules
    Estrada Munoz, Lourdes
    Diaz del Arco, Cristina
    Ortega Medina, Luis
    Fernandez Acenero, M. Jesus
    [J]. ACTA CYTOLOGICA, 2017, 61 (01) : 21 - 26
  • [25] Malignancy Rate of Thyroid Nodules Defined as Follicular Lesion of Undetermined Significance and Atypia of Undetermined Significance in Thyroid Cytopathology and Its Relation with Ultrasonographic Features
    Cuhaci, Neslihan
    Arpaci, Dilek
    Ucler, Rifki
    Yazgan, Aylin Kilic
    Kiyak, Gulten
    Yalcin, Samet
    Ersoy, Pamir Eren
    Guler, Gulnur
    Ersoy, Reyhan
    Cakir, Bekir
    [J]. ENDOCRINE PATHOLOGY, 2014, 25 (03) : 248 - 256
  • [26] Clinico-cytopathological subcategorization in thyroid nodules of atypia of undetermined significance/follicular lesion of undetermined significance using the TIRADS and Bethesda classifications
    Babajani, Amirhesam
    Rahmani, Saeed
    Raoufi, Masoomeh
    Eidgahi, Elham Shaarbaf
    Dastjerdi, Amirreza Vahid
    Behfarnia, Poya
    Khalili, Shayesteh
    Moghaddam, Noushin Afshar
    [J]. FRONTIERS IN ENDOCRINOLOGY, 2023, 14
  • [27] Different Rates of Thyroid Malignancy in Atypia of Undetermined Significance (AUS) and Follicular Lesion of Undetermined Significance (FLUS)
    Johnson, Daniel N.
    Cavallo, Allison
    Uraizee, Imran
    Tanager, Kevin S.
    Cipriani, Nicole
    Antic, Tatjana
    [J]. MODERN PATHOLOGY, 2018, 31 : 152 - 152
  • [28] Subcategorization of atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS): a study applying Thyroid Imaging Reporting and Data System (TIRADS)
    Yoon, Jung Hyun
    Kwon, Hyeong Ju
    Kim, Eun-Kyung
    Moon, Hee Jung
    Kwak, Jin Young
    [J]. CLINICAL ENDOCRINOLOGY, 2016, 85 (02) : 275 - 282
  • [29] Different Rates of Thyroid Malignancy in Atypia of Undetermined Significance (AUS) and Follicular Lesion of Undetermined Significance (FLUS)
    Johnson, Daniel N.
    Cavallo, Allison
    Uraizee, Imran
    Tanager, Kevin S.
    Cipriani, Nicole
    Antic, Tatjana
    [J]. LABORATORY INVESTIGATION, 2018, 98 : 152 - 152
  • [30] Significance of Subcategory Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Showing Both Cytologic and Architectural Atypia in Thyroid Aspiration Cytology
    Jung, Yoon Yang
    Jung, Sejin
    Lee, Hyun-Woo
    Oh, Young Lyun
    [J]. ACTA CYTOLOGICA, 2015, 59 (05) : 370 - 376
12345