Tezepelumab efficacy in patients with severe, uncontrolled asthma and comorbid nasal polyps in NAVIGATOR

被引：6
|
作者：
Menzies-Gow, Andrew [1 ]
Corren, Jonathan [2 ]
Israel, Elliot [3 ]
Welte, Tobias [4 ,5 ]
Ambrose, Christopher S. [6 ]
Cook, Bill [6 ]
Hunter, Gillian [7 ]
Llanos-Ackert, Jean-Pierre [8 ]
Colice, Gene [9 ]
机构：
[1] Royal Brompton Hosp, London, England
[2] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
[3] Harvard Med Sch, Brigham & Womens Hosp, Pulm & Crit Care Med, Allergy & Immunol, Boston, MA 02115 USA
[4] Hannover Med Sch, Dept Resp Med, Hannover, Germany
[5] Hannover Med Sch, German Ctr Lung Res, Hannover, Germany
[6] AstraZeneca, Resp & Immunol, BioPharmaceut Med, Gaithersburg, MD USA
[7] AstraZeneca, BioPharmaceut R&D, Biometr Late Stage Dev Resp & Immunol, Cambridge, England
[8] Amgen Inc, Global Med Affairs, Thousand Oaks, CA USA
[9] AstraZeneca, Late Stage Dev Resp & Immunol, BioPharmaceut R&D, Gaithersburg, MD USA
来源：
EUROPEAN RESPIRATORY JOURNAL | 2021年 / 58卷
关键词：
Asthma; Comorbidities; -; management;
D O I：
10.1183/13993003.congress-2021.PA876
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
PA876
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Efficacy Of Mepolizumab In Patients With Severe Eosinophilic Asthma And Nasal Polyps
    Liu, Mark C.
    Keene, Oliver N.
    Yancey, Steven W.
    Bratton, Daniel J.
    Albers, Frank C.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 139 (02) : AB8 - AB8
  • [42] Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma
    Menzies-Gow, Andrew
    Corren, Jonathan
    Bourdin, Arnaud
    Chupp, Geoffrey
    Israel, Elliot
    Wechsler, Michael E.
    Brightling, Christopher E.
    Griffiths, Janet M.
    Hellqvist, Asa
    Bowen, Karin
    Kaur, Primal
    Almqvist, Gun
    Ponnarambil, Sandhia
    Colice, Gene
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (19): : 1800 - 1809
  • [43] Effects of tezepelumab on asthma exacerbations, type 2 biomarkers, lung function and asthma control in patients with severe, uncontrolled asthma with and without nasal polyps: PATHWAY phase IIb study
    Emson, C.
    Corren, J.
    Salapa, K.
    Hellqvist, A.
    Parnes, J. R.
    Colice, G.
    [J]. ALLERGY, 2020, 75 : 19 - 20
  • [44] Efficacy of tezepelumab in patients with evidence of severe allergic asthma: Results from the phase 3 NAVIGATOR study
    Corren, Jonathan
    Ambrose, Christopher S. S.
    Griffiths, Janet M. M.
    Hellqvist, Asa
    Lindsley, Andrew W. W.
    Llanos, Jean-Pierre
    Colice, Gene
    Menzies-Gow, Andrew
    [J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2023, 53 (04): : 417 - 428
  • [45] Tezepelumab in Adults and Adolescents with severe, uncontrolled Asthma
    不详
    [J]. ALLERGOLOGIE, 2021, 44 (08) : 577 - 578
  • [46] Efficacy Of Tezepelumab In Patients With Severe, Uncontrolled Asthma By Specific Perennial Allergen Immunoglobulin E Thresholds
    Lindsley, Andrew
    Colice, Gene
    Martin, Neil
    Spahn, Joseph
    Martin, Nicole
    Ambrose, Chris
    Hoyte, Flavia
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2023, 151 (02) : AB18 - AB18
  • [47] Efficacy of tezepelumab in patients with severe, uncontrolled asthma, according to baseline blood eosinophil count and allergic status: results from the phase 3 NAVIGATOR study
    Menzies-Gow, A.
    Corren, J.
    Cook, B.
    Kmita, K.
    Llanos-Ackert, J.
    Colice, G.
    Ambrose, C. S.
    [J]. ALLERGY, 2021, 76 : 21 - 22
  • [48] Tezepelumab Treatment Reduced Asthma Symptomatic Days in Adults and Adolescents with Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study
    Carr, Warner
    Jain, Neal
    Ambrose, Chris
    Clarke, Nicole
    Martin, Neil
    Kmita, Kamil
    Desai, Pooja
    Llanos-Ackert, Jean-Pierre
    Ponnarambil, Sandhia
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022, 149 (02) : AB16 - AB16
  • [49] Long-term safety and efficacy of tezepelumab in adolescents with severe, uncontrolled asthma
    Brusselle, Guy
    Cook, Bill
    Lawson, Kaitlyn
    Ponnarambil, Sandhia
    Lindsley, Andrew
    Stolz, Daiana
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2023, 62
  • [50] Efficacy of Tezepelumab in Patients with Moderate-to-Severe, Uncontrolled Asthma: A Pooled Analysis of the Phase 2b PATHWAY and Phase 3 NAVIGATOR Studies
    Ambrose, Chris
    Menzies-Gow, Andrew
    Cook, Bill
    Hellqvist, Asa
    Roseti, Stephanie
    Molfino, Nestor
    Llanos-Ackert, Jean-Pierre
    Colice, Gene
    Corren, Jonathan
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2022, 149 (02) : AB16 - AB16
12345