The mirror-type internal symmetry in the primary structure of proteins: Detection and functional role - (Review)

被引:1
|
作者
Shpakov, AO [1 ]
机构
[1] Russian Acad Sci, Sechenov Inst Evolutionary Physiol & Biochem, St Petersburg 196140, Russia
关键词
D O I
10.1023/A:1017570620437
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review summarized the data obtained by the author in studies on internal symmetry of the mirror type in primary structures of proteins. The methods for detection of symmetric segments in amino acid sequences are analyzed: (1) the method based on analysis of sequences of roots of amino acid codons; (2) the dot matrix method; (3) the method of internal symmetry scanning. The results of studies of internal symmetry in enzymes and signaling proteins are presented. The probable role of the internal symmetry in the structural-functional organization of proteins is discussed.
引用
收藏
页码:685 / 700
页数:16
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