The mirror-type internal symmetry in the primary structure of proteins: Detection and functional role - (Review)

This review summarized the data obtained by the author in studies on internal symmetry of the mirror type in primary structures of proteins. The methods for detection of symmetric segments in amino acid sequences are analyzed: (1) the method based on analysis of sequences of roots of amino acid codons; (2) the dot matrix method; (3) the method of internal symmetry scanning. The results of studies of internal symmetry in enzymes and signaling proteins are presented. The probable role of the internal symmetry in the structural-functional organization of proteins is discussed.