Ceramide kinase and ceramide-1-phosphate

被引：25

作者：

Wijesinghe, Dayanjan S. ^{[1
]}

Lamour, Nadia F.

Gomez-Munoz, Antonio

Chalfant, Charles E.

机构：

[1] Virginia Commonwealth Univ, Sch Med, Dept Biochem & Mol Biol, Richmond, VA 23298 USA

[2] Univ Basque Country, Fac Sci & Technol, Dept Biochem & Mol Biol, Bilbao, Spain

[3] Hunter Holmes McGuire Vet Adm Med Ctr, Res & Dev, Richmond, VA USA

来源：

LIPIDOMICS AND BIOACTIVE LIPIDS: LIPIDS AND CELL SIGNALING | 2007年 / 434卷

关键词：

D O I：

10.1016/S0076-6879(07)34015-9

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

it has been over a decade since the sphingolipid ceramide-1-phosphate (C1P) was described. Until recently, only sparse reports on possible biological functions for this lipid have been published. A large number of reports have now surfaced demonstrating distinct biological mechanisms regulated by C1P produced from ceramide kinase (CERK). In the following methods chapter, the methodologies for examining CERK function in vitro and in cells are outlined in detail. The methodologies for examining C1P levels and the use of exogenous C1P on cells to observe lipid specific effects on a particular biology are also detailed.

引用

页码：265 / +

页数：29

共 50 条

[1] CERAMIDE KINASE, CERAMIDE-1-PHOSPHATE: ROLES AND REGULATION
Bornancin, Frederic
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2010, 382 : 9 - 9
[2] Ceramide kinase, ceramide-1-phosphate: Roles and implication in phagocytosis and phagolysosomal fusion
Hinkovska-Galcheva, VT
Kindzelski, AL
Huang, JB
Clark, A
Shanley, T
Shayman, J
Petty, H
Boxer, L
FASEB JOURNAL, 2006, 20 (04): : A484 - A484
[3] SYNTHESIS OF CERAMIDE-1-PHOSPHATE
BUSHNEV, AS
KARPYSHEV, NN
ZVONKOVA, EN
EVSTIGNEEVA, RP
BIOORGANICHESKAYA KHIMIYA, 1979, 5 (09): : 1381 - 1384
[4] Translocation and activation of sphingosine kinase 1 by ceramide-1-phosphate
Nishino, Shohei
Yamashita, Hisahiro
Tamori, Mizuki
Mashimo, Masato
Yamagata, Kazuyuki
Nakamura, Hiroyuki
Murayama, Toshihiko
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 120 (04) : 5396 - 5408
[5] Ceramide kinase and the ceramide-1-phosphate/cPLA2 interaction as a therapeutic target
Lamour, Nadia F.
Chalfant, Charles E.
CURRENT DRUG TARGETS, 2008, 9 (08) : 674 - 682
[6] A Comparison Of Ceramide And Ceramide-1-phosphate Miscibility In Phosphatidylcholine Bilayers
Morrow, Michael R.
Helle, Anne
Perry, Joshua
Vattulainen, Ilpo
Wiedmer, Susanne K.
Holopainen, Juha M.
BIOPHYSICAL JOURNAL, 2009, 96 (03) : 162A - 163A
[7] Ceramide-1-phosphate directly regulates sphingosine kinase 1 activity
Nishino, Shohei
Yamashita, Hisahiro
Nakamura, Hiroyuki
Murayama, Toshihiko
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2017, 133 (03) : S141 - S141
[8] Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice
Graf, Christine
Niwa, Satoru
Mueller, Matthias
Kinzel, Bernd
Bornancin, Frederic
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 373 (01) : 159 - 163
[9] Effects of Glycerophospholipids on Ceramide Kinase Activity: Cardiolipin-Affected Cellular Formation of Ceramide-1-phosphate
Matsuzaki, Wataru
Takahashi, Hiromasa
Nakamura, Hiroyuki
Murayama, Toshihiko
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2016, 39 (10) : 1708 - 1717
[10] Ceramide-1-phosphate stimulates carbohydrate metabolism
Ordonez, M.
Ouro, A.
Arana, L.
Rivera, I. G.
Gangoiti, P.
Trueba, M.
Gomez-Munoz, A.
FEBS JOURNAL, 2012, 279 : 152 - 152

← 1 2 3 4 5 →