SAW based Mass-loading Biosensor for DNA Detection

被引：0
|
作者：
Cai, Hualin [1 ]
Zhou, Changjian [1 ]
Zhang, Yihan [1 ]
Yang, Yi [1 ]
Ren, Tianling [1 ]
Guo, Cangran [2 ]
Liu, Jing [2 ]
机构：
[1] Tsinghua Univ, Inst Microelect, Beijing, Peoples R China
[2] Tsinghua Univ, Dept Biomed Engn, Beijing, Peoples R China
来源：
2013 IEEE INTERNATIONAL CONFERENCE OF ELECTRON DEVICES AND SOLID-STATE CIRCUITS (EDSSC) | 2013年
关键词：
SAW sensor; DNA detection; high sensitivity;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
In this paper, a Surface Acoustic Wave (SAW) biosensor with gold coated delay area detecting DNA sequences is proposed. By well-designed procedures of device structure and parameters, we manufactured a simple and high-performance SAW on LiNbO3 substrate. The SA W biosensor with gold delay area that is connected to PCB board through bonding wires could be used for the direct measurement and sonic path comparative measurement of SII parameter by using Network Analyzer. The device works near 6SMHz. The loading mass of DNA probe and target DNA sequences are obtained from frequency shift, which is big enough in this work due to an effective biological treatment method. The testing result shows that the SAW sensor has a high sensitivity of 1.2pg/mllHz.
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页数：2
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