The Kallikrein-related serine peptidase, KLK4, regulates the TGFβ1 pathway in the tumour-stroma microenvironment in prostate cancer

被引：0
|
作者：
Fuhrman-Luck, R. [1 ,2 ]
Stansfield, S. [1 ]
Hastie, M. [3 ]
Stoll, T. [3 ]
Stephens, C. [1 ,2 ]
Loessner, D. [1 ]
Lehman, M. [1 ,2 ]
Nelson, C. [1 ,2 ]
Gorman, J. [3 ]
Clements, J. A. [1 ,2 ]
机构：
[1] Inst Hlth & Biomed Innovat, Brisbane, Qld, Australia
[2] Queensland Univ Technol, Translat Res Inst, Australian Prostate Canc Res Ctr Queensland, Woolloongabba, Qld 4102, Australia
[3] Queensland Inst Med Res, Herston, Qld 4006, Australia
来源：
CLINICAL & EXPERIMENTAL METASTASIS | 2015年 / 32卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
21
引用
收藏
页码：197 / 197
页数：1
相关论文
共 38 条
  • [21] Low mRNA expression levels of kallikrein-related peptidase 4 (KLK4) predict short-term relapse in patients with laryngeal squamous cell carcinoma
    Foteinou, Emmanouela
    Kontos, Christos K.
    Giotakis, Aris I.
    Scorilas, Andreas
    BIOLOGICAL CHEMISTRY, 2014, 395 (09) : 1051 - 1062
  • [22] Kallikrein-related peptidase-4 initiates tumor-stroma interactions in prostate cancer through protease-activated receptor-1
    Wang, Wenbin
    Mize, Gregory J.
    Zhang, Xiaotun
    Takayama, Thomas K.
    INTERNATIONAL JOURNAL OF CANCER, 2010, 126 (03) : 599 - 610
  • [23] Elevated levels of both microRNA 378 (miR-378) and kallikrein-related peptidase 4 (KLK4) mRNA are associated with an unfavorable prognosis in triple-negative breast cancer
    Gong, Weiwei
    Zhu, Caixia
    Liu, Yueyang
    Muckenhuber, Alexander
    Bronger, Holger
    Scorilas, Andreas
    Kiechle, Marion
    Dorn, Julia
    Magdolen, Viktor
    Dreyer, Tobias
    AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 13 (03): : 1594 - 1606
  • [24] Potential role of multiple members of the kallikrein-related peptidase family of serine proteases in activating latent TGFβ1 in semen
    Emami, Nashmil
    Diamandis, Eleftherios P.
    BIOLOGICAL CHEMISTRY, 2010, 391 (01) : 85 - 95
  • [25] Prostate Cancer-Associated Kallikrein-Related Peptidase 4 Activates Matrix Metalloproteinase-1 and Thrombospondin-1
    Fuhrman-Luck, Ruth A.
    Stansfield, Scott H.
    Stephens, Carson R.
    Loessner, Daniela
    Clements, Judith A.
    JOURNAL OF PROTEOME RESEARCH, 2016, 15 (08) : 2466 - 2478
  • [26] Kallikrein-related peptidase 4 induces plasticity and cancer-associated fibroblast features in prostate stromal cells
    Kryza, T.
    Fuhrman-Luck, R.
    Stephens, C.
    Lawrence, M.
    Hooper, J.
    Dong, Y.
    Risbridger, G.
    Clements, J.
    CLINICAL & EXPERIMENTAL METASTASIS, 2019, 36 (02) : 141 - 141
  • [27] Discovery of novel transcripts of the human tissue kallikrein (KLK1) and kallikrein-related peptidase 2 (KLK2) in human cancer cells, exploiting Next-Generation Sequencing technology
    Adamopoulos, Panagiotis G.
    Kontos, Christos K.
    Scorilas, Andreas
    GENOMICS, 2019, 111 (04) : 642 - 652
  • [28] Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells
    Kryza, Thomas
    Silva, Lakmali M.
    Bock, Nathalie
    Fuhrman-Luck, Ruth A.
    Stephens, Carson R.
    Gao, Jin
    Samaratunga, Hema
    Lawrence, Mitchell G.
    Hooper, John D.
    Dong, Ying
    Risbridger, Gail P.
    Clements, Judith A.
    MOLECULAR ONCOLOGY, 2017, 11 (10) : 1307 - 1329
  • [29] Paclitaxel Resistance and Multicellular Spheroid Formation Are Induced by Kallikrein-Related Peptidase 4 in Serous Ovarian Cancer Cells in an Ascites Mimicking Microenvironment
    Dong, Ying
    Stephens, Carson
    Walpole, Carina
    Swedberg, Joakim E.
    Boyle, Glen M.
    Parsons, Peter G.
    McGuckin, Michael A.
    Harris, Jonathan M.
    Clements, Judith A.
    PLOS ONE, 2013, 8 (02):
  • [30] Direct Progesterone Receptor and Indirect Androgen Receptor Interactions with the Kallikrein-Related Peptidase 4 Gene Promoter in Breast and Prostate Cancer
    Lai, John
    Myers, Stephen A.
    Lawrence, Mitchell G.
    Odorlco, Dimitri M.
    Clements, Judith A.
    MOLECULAR CANCER RESEARCH, 2009, 7 (01) : 129 - 141
1234