A glucosylceramide with antimicrobial activity from the edible mushroom Pleurotus citrinopileatus

被引：14

作者：

Meng, Tian-Xiao ^{[1
]}

Ishikawa, Hiroya ^{[2
]}

Shimizu, Kuniyoshi ^{[1
]}

Ohga, Shoji ^{[1
]}

Kondo, Ryuichiro ^{[1
]}

机构：

[1] Kyushu Univ, Fac Agr, Dept Agroenvironm Sci, Higashi Ku, Fukuoka 8128581, Japan

[2] Fukuoka Womens Univ, Fac Human Environm Sci, Dept Nutr & Hlth Sci, Fukuoka 8138529, Japan

来源：

JOURNAL OF WOOD SCIENCE | 2012年 / 58卷 / 01期

关键词：

Pleurotus citrinopileatus; Glucosylceramide; Antimicrobial activity; Tamogitake; SPHINGOLIPIDS; CEREBROSIDES; CONSTITUENTS; PURIFICATION; CELLS;

D O I：

10.1007/s10086-011-1213-y

中图分类号：

S7 [林业];

学科分类号：

0829 ; 0907 ;

摘要：

The golden oyster mushroom Pleurotus citrinopileatus is a popular edible mushroom with multifunctional biological activities, but there are a limited number of previous studies on its chemical composition. This is the first report of the isolation of glucosylceramide with antimicrobial activity from the fruiting body of this mushroom. This compound was identified as 1-O-beta-d-glucopyranosyl-(2S,3R,4E,8E)-2-[(2R)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol. The IC50 value of this compound for the growth of Escherichia coli and Staphylococcus aureus was 275.1 mu M (200 mu g/ml) and 323.2 mu M (235 mu g/ml), respectively.

引用

页码：81 / 86

页数：6

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