BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation

被引:0
|
作者
Chan, Lai N. [1 ,2 ]
Hurtz, Christian [3 ]
Robinson, Mark E. [1 ,2 ]
Leveille, Etienne [1 ,2 ]
Geng, Huimin [4 ]
Caeser, Rebecca [5 ]
Xu, Liang [6 ]
Kume, Kohei [7 ,8 ]
Xiao, Gang [6 ]
Muschen, Markus [1 ,2 ]
机构
[1] Yale Univ, Ctr Mol & Cellular Oncol, New Haven, CT USA
[2] Yale Univ, Dept Immunobiol, New Haven, CT USA
[3] Temple Univ, Lewis Katz Sch Med, Philadelphia, PA 19122 USA
[4] Univ Calif San Francisco, Dept Lab Med, San Francisco, CA USA
[5] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10021 USA
[6] Zhejiang Univ, Coll Life Sci, Hangzhou, Peoples R China
[7] Yale Univ, Ctr Mol & Cellular Oncol, Duarte, CA USA
[8] Yale Univ, Dept Immunobiol, Duarte, CA USA
关键词
D O I
10.1182/blood-2022-169946
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:9177 / 9178
页数:2
相关论文
共 50 条
  • [41] Contribution of estrogen receptor α to oncogenic K-Ras-mediated NIH3T3 cell transformation and its implication for escape from senescence by modulating the p53 pathway
    Kato, K
    Horiuchi, S
    Takahashi, A
    Ueoka, Y
    Arima, T
    Matsuda, T
    Kato, H
    Nishida, J
    Nakabeppu, Y
    Wake, N
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (13) : 11217 - 11224
  • [42] Outcomes of Patients with Limited-Stage Aggressive Large B-Cell Lymphoma with MYC Rearrangement with and without BCL2 and/or BCL6 Rearrangements: A Retrospective Analysis from 15 US Academic Centers
    Kothari, Shalin K.
    Li, Shaoying
    Medeiros, L. Jeffrey
    Ayers, Emily C.
    Landsburg, Daniel J.
    Bond, David A.
    Maddocks, Kami J.
    Giri, Anshu
    Hess, Brian T.
    Pham, Luu Q.
    Advani, Ranjana
    Liu, Yang
    Barta, Stefan Klaus
    Vose, Julie M.
    Churnetski, Michael C.
    Cohen, Jonathon B.
    Burkart, Madelyn
    Karmali, Reem
    Zurko, Joanna
    Mehta, Amitkumar
    Olszewski, Adam J.
    Lee, Sarah S.
    Hill, Brian T.
    Burns, Timothy F.
    Lansigan, Frederick
    Rabinovich, Emma
    Peace, David
    Groman, Adrienne
    Attwood, Kris
    Hernandez-Ilizaliturri, Francisco J.
    Torka, Pallawi
    BLOOD, 2018, 132
  • [43] BCL-6 protein expression in large B-cell gastrointestinal lymphomas: How to distinguish high-grade MALT lymphoma from non-MALT counterpart
    Ree, HJ
    Kim, CW
    Charney, D
    Ko, YH
    Kwon, KY
    LABORATORY INVESTIGATION, 1997, 76 (01) : 773 - 773
  • [44] Prognostic Impact of Myc/Bcl6 Co-Rearrangement and MYC/BCL6 Co-Expression in De Novo Diffuse Large B-Cell Lymphoma: A Report from the International DLBCL Rituximab-CHOP Consortium Program Study
    Hu, S.
    Tzankov, A.
    Visco, C.
    Orazi, O.
    Bhagat, G.
    Hsi, E. D.
    Ponzoni, M.
    Piris, M. A.
    Moller, M. B.
    Medeiros, L. J.
    Young, K. H.
    MODERN PATHOLOGY, 2013, 26 : 333A - 333A
  • [45] Prognostic Impact of Myc/Bcl6 Co-Rearrangement and MYC/BCL6 Co-Expression in De Novo Diffuse Large B-Cell Lymphoma: A Report from the International DLBCL Rituximab-CHOP Consortium Program Study
    Hu, S.
    Tzankov, A.
    Visco, C.
    Orazi, O.
    Bhagat, G.
    Hsi, E. D.
    Ponzoni, M.
    Piris, M. A.
    Moller, M. B.
    Medeiros, L. J.
    Young, K. H.
    LABORATORY INVESTIGATION, 2013, 93 : 333A - 333A
  • [46] Bcl-6 and CD10 paraffin section immunohistochemistry on bone marrow core biopsies to distinguish follicular lymphoma from other small B-cell non-Hodgkin lymphomas
    Velankar, M
    Kansal, R
    Finn, WG
    Valdez, R
    Ross, CW
    Schnitzer, B
    MODERN PATHOLOGY, 2002, 15 (01) : 268A - 269A
  • [47] Bcl-6 and CD10 paraffin section immunohistochemistry on bone marrow core biopsies to distinguish follicular lymphoma from other small B-cell non-Hodgkin lymphomas
    Velankar, M
    Kansal, R
    Finn, WG
    Valdez, R
    Ross, CW
    Schnitzer, B
    LABORATORY INVESTIGATION, 2002, 82 (01) : 268A - 269A
  • [48] A Double Hit CD10-Negative B-Cell Lymphoma with t(3;8)(q27;q24) Leading to Juxtaposition of the BCL6 and MYC Loci Associated with Good Clinical Outcome
    Sanders, Lucinda
    Jayne, Sandrine
    Kennedy, Ben
    Miall, Fiona
    Aukema, Sietse M.
    Siebert, Reiner
    Wagner, Simon D.
    Dyer, Martin J. S.
    CASE REPORTS IN HEMATOLOGY, 2014, 2014
  • [49] Clinical and Biological significance of MYC/BCL6 dual gene rearrangements and protein co-expression in de novo diffuse large B-cell lymphoma: a report from the International DLBCL Rituximab-CHOP Consortium Program
    Ye, Qinng
    Xu-Monette, Zijun Y.
    Hu, Shimin
    Tzankov, Alexander
    Gisin, Nora
    Visco, Carlo
    Montes-Moreno, Santiago
    Dybkwr, Karen
    Chiu, April
    Orazi, Attilio
    Zu, Youli
    Bhagat, Govind
    Richards, Kristy L.
    Hsi, Eric D.
    Choi, William W. L.
    van Krieken, J. Han
    Huh, Jooryung
    Ponzoni, Maurilio
    Ferreri, Andres J. M.
    Moller, Michael B.
    Go, Ronald S.
    Winter, Jane N.
    Piris, Miguel A.
    Medeiros, L. Jeffrey
    Young, Ken H.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2015, 15 : S228 - S228
  • [50] Allogeneic cell therapy in murine B-cell leukemia (BCL1): 1. Alloimmune-mediated graft-versus-leukemia (GVL) effects induced by unmodified and in vitro rIL-2-activated bone marrow and lymphocytes from different lymphoid compartments
    Weiss, L
    Reich, S
    Slavin, S
    CYTOKINES CELLULAR & MOLECULAR THERAPY, 1999, 5 (03) : 145 - 152